Sentences with phrase «in the large cohort study»

The aim of this new study was to determine whether 2D: 4D was associated with the risk of severe knee or hip OA requiring total joint replacement in a large cohort study.

In the large cohort study mentioned above, the most common allergy was peanut with a prevalence of 2.6 %, followed by milk at 2.2 %, egg at 1.8 %, shellfish at 1.5 % and soy at 0.7 %.

Methods In a large cohort study, the Avon Longitudinal Study of Parents and Children (n = 14541 pregnancies), we aimed to (i) investigate the relative influences of parental postnatal depression and marital conflict on child outcomes and to attempt to determine the pathway (s) of risk; (ii) investigate the impact of two types of antenatal stress (parental depression and marital conflict) on child outcomes; and (iii) determine the relative contributions of antenatal and postnatal risk.

Not exact matches

Three years ago millennials surpassed Gen Xers to become the single largest cohort working in the United States, according to a study conducted by PEW Research.

A study published in 2000 by the ELCA revealed that of the cohort of newly minted pastors, 71 percent placed constraints upon where they could move due to the needs or desires of a spouse; 58 percent restricted their first call to a location in or near a large city; 36 percent were opposed to serving in a small congregation; and 32 percent were opposed to serving in a rural setting.

Last week, we posted to the site a group of four articles about a peer - reviewed study in the Journal of Neurosurgery showing that football helmet design affected concussion risk among a large group (or what scientists call a «cohort») of college football players.

Most studies of homebirth in other countries have found no statistically significant differences in perinatal outcomes between home and hospital births for women at low risk of complications.36, 37,39 However, a recent study in the United States showed poorer neonatal outcomes for births occurring at home or in birth centres.40 A meta - analysis in the same year demonstrated higher perinatal mortality associated with homebirth41 but has been strongly criticised on methodological grounds.5, 42 The Birthplace in England study, 43 the largest prospective cohort study on place of birth for women at low risk of complications, analysed a composite outcome, which included stillbirth and early neonatal death among other serious morbidity.

An UpToDate review on «Planned home birth» (Declercq and Stotland, 2015) stated that «Large cohort studies using intent - to - treat analysis of midwife - attended, planned, out - of - hospital birth of low - risk women in developed countries have reported reduced rates of cesarean birth, perineal lacerations, and medical interventions, and similar rates of maternal and early perinatal morbidity and mortality compared to planned hospital birth.

This also was found in a large, retrospective cohort study of 15,759 nulliparous women even in a group of women whose second stage progressed beyond 4 hours (29).

«For this large cohort of women who planned midwife - led home births in the United States, outcomes are congruent with the best available data from population - based, observational studies that evaluated outcomes by intended place of birth and perinatal risk factors.

Studies also suggest a potential role for selected probiotics in atopic dermatitis prevention, and future studies will need to standardize the probiotic strain as well as amount used in a larger cohort of pregnant women in order to better assess these eStudies also suggest a potential role for selected probiotics in atopic dermatitis prevention, and future studies will need to standardize the probiotic strain as well as amount used in a larger cohort of pregnant women in order to better assess these estudies will need to standardize the probiotic strain as well as amount used in a larger cohort of pregnant women in order to better assess these effects.

Commenting on the study, ESMO spokesperson Dirk Arnold, MD, PhD, from Instituto CUF de Oncologia in Lisbon, Portugal, said «this large population - based cohort - control study impressively confirms the hypothesis of an association of colorectal polyps with diets and other life - style factors.

While further study of larger patient groups with longer follow - up times is needed for this cohort of prostate cancer patients, this study is pivotal in providing evidence for change in practice.»

Additional studies in larger cohorts will be needed to validate these findings, and more biomarkers will be needed to get the completely accurate set needed to screen the general population with the long term goal of identifying precursor lesions before they become malignant.

Thompson and others claimed that would have endangered large investments in disease registries, cohort studies, and biobanks.

Data was gathered on 2,424 participants of the Rotterdam study, a large population - based cohort study including participants 45 years or older living in a suburb of Rotterdam, The Netherlands.

Several large cohort studies of medical x-ray technicians and nuclear industry workers suggest a slight increase in cancer risk at exposures below 100 mSv, Shore says.

To identify the relevant mutations the scientists analyzed the blood samples of 1,858 men from three independent cohorts in Europe and North America: the Swiss arm of the European Randomized Study for Prostate Cancer Screening, the large American Screening trial, Prostate, Lung, Colorectal, and Ovarian (PLCO), Princess Margaret Cancer Centre (University Health Network) and Mount Sinai Hospital (Sinai Health System) in Toronto.

Our large cohort study confirms that these are also risky conditions for heart attack patients in the current era.»

A phase II basket study is ongoing to determine whether these early results can be confirmed in a much larger cohort of patients.

The Chronic Hepatitis Cohort Study is an analysis of records from a large, geographically and racially diverse group of 9,783 patients receiving care at four large U.S. health systems: Henry Ford Health System in Detroit; Kaiser Permanente Northwest in Portland, Oregon; Kaiser Permanente in Honolulu and Geisinger Health System in Danville, Pennsylvania.

Findings from this UK cohort are confirmed by evidence for adult - onset ADHD world - wide: a study from Brazil will be published by JAMA Psychiatry alongside this research, which also identified a large proportion of adults with ADHD as not having the disorder in childhood.

Young adults with thinner cortex in particular brain regions are more impulsive during a decision - making task than teens with thicker cortex, according to a large correlational study of adolescents from the Philadelphia Neurodevelopmental Cohort.

This is the largest cohort study to analyze changes in rates of pre-eclampsia in the U.S.

From this survey data, NASA's James Webb Space Telescope as well as large ground - based observatories will be able to further characterize the targets, making it possible for the first time to study the masses, sizes, densities, orbits, and atmospheres of a large cohort of small planets, including a sample of rocky worlds in the habitable zones of their host stars.

Dr. Zhang points out that the unique value of this study derives from the ability to perform longitudinal assessments of cognition in PD patients over a long time period and access to data from a large cohort that began when patients were in the earliest stage of disease.

In this 9 - centre, large ongoing cohort study, researchers evaluated the survival in Caucasian CHB patients with or without cirrhosis who have been receiving ETV or TDIn this 9 - centre, large ongoing cohort study, researchers evaluated the survival in Caucasian CHB patients with or without cirrhosis who have been receiving ETV or TDin Caucasian CHB patients with or without cirrhosis who have been receiving ETV or TDF.

Dr Matt Hurles, who led the study from the Sanger Institute, said: «This study has the largest cohort of such families in the world, and harnesses the power of the NHS, with 200 clinical geneticists and 4,000 patients.

Researchers expect the data presented in this study to fuel the formation of large national and international research consortiums to conduct comprehensive, systematic analysis of inherited (germline) genome data in large cohorts of uveal melanoma patients.

The prospective study included 23,928 participants without coronary heart disease from Reasons for Geographic and Racial Differences in Stroke (REGARDS), a large biracial population - based cohort study.

For this population - based research, investigators pooled data from large cohort studies conducted in Asia and included demographic and risk factor information collected in seven Asian regions from the early 1960s through the late 1990s (although most of the studies enrolled participants after the mid-1980s).

Conducting a cross-sectional study of a large cohort of patients with different levels of cognitive impairment and different disease stages, the researchers found that the amounts of a TREM2 fragment in the cerebrospinal fluid were highest during early stages characterized by mild cognitive impairment symptoms.

The team is now applying for grant funding to expand their study in a larger cohort across multiple sites.

Several countries, including the United Kingdom and Estonia, have assembled similar studies of large groups of people, or cohorts, that collect DNA and health information on volunteers in repositories, sometimes called «biobanks.»

This study represents the largest reported cohort of CRC patients diagnosed in this age range in the U.S.

They are now in their 25th year of follow - up as part of a large, prospective cohort study.

Researchers believe it is the largest epigenetic study yet for any single cancer type and, importantly, the first to use a large cohort of primary patient tumor tissues instead of cell lines grown in the laboratory.

The Columbia researchers with colleagues in Finland conducted an analysis of data from the Finnish Prenatal Study of Schizophrenia, a large, national birth cohort with an extensive bio-bank.

Our study is one of the largest to explore the efficacy and safety of anti-TNF therapy in a large independent cohort of JDM patients.»

Of the dozen of these metabolites that were measured in cohorts from the longitudinal Framingham Heart Study (the long - term 1948 study to identify the common contributive factors of cardiovascular disease by following its development in a large subject group) levels of glycerol turned out to be «significantly correlated» with resting heart rate, another indicator of fitness, as measured in the sStudy (the long - term 1948 study to identify the common contributive factors of cardiovascular disease by following its development in a large subject group) levels of glycerol turned out to be «significantly correlated» with resting heart rate, another indicator of fitness, as measured in the sstudy to identify the common contributive factors of cardiovascular disease by following its development in a large subject group) levels of glycerol turned out to be «significantly correlated» with resting heart rate, another indicator of fitness, as measured in the studystudy.

Researchers analyzed data from a large national birth cohort of pregnant women who participated in the Finnish Prenatal Study of Schizophrenia and their offspring from the Finnish Maternity Cohort, which archived over 1 million prenatal serum specimens sincecohort of pregnant women who participated in the Finnish Prenatal Study of Schizophrenia and their offspring from the Finnish Maternity Cohort, which archived over 1 million prenatal serum specimens sinceCohort, which archived over 1 million prenatal serum specimens since 1983.

She and her team had previously analyzed blood samples of children in a biobank established by Professor Anette - Gabriele Ziegler, director of the IDF, within the framework of large - scale cohort studies.

In this study, researchers used blood samples collected several years before breast cancer development from two large UK cohorts of women — the MRC National Survey of Health and Development and the UK Collaborative Trial of Ovarian Cancer Screening.

«Metabolomics is now often used to accompany large genomic cohort studies from biobanks, to correlate genotype and genomic variants with specific phenotypes, to complement nutritional studies monitoring food components or endogenous metabolites, or to support measurements in epidemiology studies,» says Andreas Huhmer, director of proteomics and metabolomics marketing at Thermo Fisher Scientific, headquartered in Waltham, Massachusetts.

The NYGC and its founding member institutions are conducting additional studies involving Watson to help accelerate the discovery of potentially actionable sequence variants in various types of cancer, including an ongoing study that involves DNA and RNA from a larger cohort of glioblastoma patients, and a study of 200 patients with different types of cancer.

The LALES study, conducted among 4,876 Latinos in Los Angeles with a mean age cohort of 54.8 years old, indicates that Latinos diagnosed with bilateral AMD with large drusen (the lipids or fatty proteins that are yellow deposits under the retina) and depigmentation as well as a more severe AMD had a substantially lower health - related quality of life as compared to those with AMD lesions in only one eye.

«We're looking forward to longer - term results to come in the next five years from various ongoing observational studies,» Dr. Arterburn said: The Utah Obesity Study, the Michigan Bariatric Surgery Collaborative, and large cohorts from Veterans Affairs health system and the HMO Research Network (including Group Health) and should yield important long - term information comparing the efficacy, safety, and costs of surgical and non-surgical care for severe obesity.

Samples from large, well - phenotyped cohorts have always been in high demand for genetic studies.

Yet a pilot study of 200, 500, or 1,000 samples may be feasible, and may uncover results that can be replicated in the larger cohort.

Yet the only way we'll make progress is to study them in large cohorts numbering thousands of samples.