Not exact matches
Bhatia is now working on
increasing the number of
hepatocytes present on the two - centimetre graft, to ensure that it is useful in the clinic.
Leukemic cells can feed themselves through
increased secretion of
hepatocyte growth factor (HGF), which then activates its receptor, MET, to promote growth.
When blood glucose levels are high,
hepatocytes respond to insulin by
increasing glycogen storage, decreasing gluconeogenesis, and decreasing glycogenolysis.
These results support the notion that the
increased clearance of ApoC - III — depleted [3H] TRLs in Ndst1fl / fl Alb - Cre + mice, and not in Ldlr — / — Lrp1fl / fl Alb - Cre + mice, is a consequence of
increased uptake by LDLR / LRP1 on
hepatocytes.
Binding and uptake of radiolabeled ApoC - III — depleted TRLs was significantly
increased in
hepatocytes isolated from Ndst1fl / fl Alb - Cre + mice (i.e., in mice expressing both LDLR and LRP1) when compared with ApoC - III — bearing TRLs (Figure 10).
The two, key, active constituents in milk thistle, silymarin and silybinin,
increase the uptake of hepatic glutathione, reduce oxidative stress and stimulate
hepatocyte protein synthesis.