Sentences with phrase «induced apoptosis»

The results showed, «Lauric acid induced apoptosis in Caco - 2 (p < 0.05) and IEC - 6 cells» while butyrate did not.

As a result, the animals treated with blueberry, spinach, or spirulina were reported to have reduced ischemia / reperfusion - induced apoptosis and cerebral infraction.

We found that ellagic acid at a concentration of 10 -LRB--5) M induced G arrest within 48 hours, inhibited overall cell growth and induced apoptosis in CaSki cells after 72 hours of treatment.

In an in vitro study, vanillin induced apoptosis and arrested the cell cycle of human colorectal cancer cells, and some researchers think vanillin could reduce the metastatic potential (ability to spread to other parts of the body) of human cancer cells in vivo, too.

Targeting autophagy potentiates chemotherapy - induced apoptosis and proliferation inhibition in hepatocarcinoma cells.

Recently, our lab has discovered that a member of Kruppel - like family of transcription factors, KLF9, regulates bortezomib - induced apoptosis in MM cells.

Gadd45b mediates Fas - induced apoptosis by enhancing the interaction between p38 and retinoblastoma tumor suppressor

Loss of Runx2 sensitizes osteosarcoma to chemotherapy - induced apoptosis, accepted, British Journal of Cancer.

Gadd45b plays a role in cell cycle arrest, and it is a positive mediator in Fas - induced apoptosis when a DNA injury appeared in nonneoplasic cells [28].

Here, we report that suboptimal IVC altered the gene expression of adult male testis and induced apoptosis.

p38 kinase regulates nitric oxide - induced apoptosis of articular chondrocytes by accumulating p53 via NFkappa B - dependent transcription and stabilization by serine 15 phosphorylation.

Manfe V, Biskup E, Rosbjerg A, Kamstrup M, Skov AG, Lerche CM, Lauenborg BT, Odum N and Gniadecki R. miR - 122 regulates p53 / Akt signalling and the chemotherapy - induced apoptosis in cutaneous T - cell lymphoma.

In addition, transfection of constitutively active AKT or PLK1 partially rescued cells from 15d - PGJ2 - induced apoptosis, suggesting crucial roles for both pathways in the anti-cancer effects of 15d - PGJ2.

Figure 2 (middle line) shows that 50 nmol kahweol induced apoptosis in a small percentage of cells but this effect did not seem to be endothelial cell specific, since only few apoptotic nuclei corresponded to endothelial cells.

Given the apoptosome's critical role in the execution of stress - induced apoptosis, these studies provide key insights into the mechanisms by which many, if not most, chemotherapeutic agents induce cell death.

Li W, Fan JG, Bertino JR: Flavopiridol enhances doxorubicin - induced apoptosis in human sarcoma cells lacking Rb protein.

Phthalates inhibit tamoxifen - induced apoptosis in MCF - 7 human breast cancer cells.

Case Western Reserve University School of Medicine Stress signaling inhibitors potentiate genotoxin - induced apoptosis in a human colon tumor model

Hong - Gang Wang, PhD (D Club) Lois High Bestler Professor of Pediatrics and Pharmacology; Director, Pediatrics Molecular Oncology Program «Ca2 + induced apoptosis through calcineurin dephosphorylation of BAD» Science, April 1999 860 citations, Web of Science, April 1, 2017

AXL mediates resistance to TRAIL - induced cell death in esophageal adenocarcinoma (55); it remains to be determined whether ABL - mediated protection from TRAIL - induced apoptosis in breast cancer cells is mediated by AXL or other targets.

Both in vitro and in vivo, the combination of decitabine and chidamide induced apoptosis of Jurkat cells bearing the KMT2D mutant.

The role of enoyl - CoA hydratase short chain 1 and peroxiredoxin 3 in PP2 - induced apoptosis in human breast cancer MCF - 7 cells.

Targeting of the c - Abl tyrosine kinase to mitochondria in endoplasmic reticulum stress - induced apoptosis.

MEK kinase 1, a substrate for DEVD - directed caspases, is involved in genotoxin - induced apoptosis.

In the bone marrow microenvironment, CLL cells are protected from spontaneous or drug - induced apoptosis, resulting in resistance to conventional chemotherapy.

Protein kinase Cα and ζ differentially regulate death - inducing signaling complex formation in cigarette smoke extract - induced apoptosis.

Matrix metalloproteinase - 2 contributes to tumor necrosis factor alpha induced apoptosis in cultured rat cardiac myocytes.

The SUMO ligase PIAS1 regulates UV - induced apoptosis by recruiting Daxx to SUMOylated foci % U http://jcs.biologists.org/content/early/2012/09/07/jcs.110825.short.

Additional studies are attempting to determine if the transgene expression of various anti-apoptotic genes can protect T cells from tumor - induced apoptosis.

Synergistic effect of radachlorin mediated photodynamic therapy on propolis induced apoptosis in AMC - HN - 4 cell lines via caspase dependent pathway.

MicroRNA - 15a inhibition protects against hypoxia / reoxygenation - induced apoptosis of cardiomyocytes by targeting mothers against decapentaplegic homolog 7.

p38 MAP kinase mediates arsenite - induced apoptosis through FOXO3a activation and induction of Bim transcription.

Expression of sulfotransferase isoform 1A1 (SULT1A1) in breast cancer cells significantly increases 4 - hydroxytamoxifen - induced apoptosis.

Live fluorescence and transmission - through - dye microscopic study of actinomycin D - induced apoptosis and apoptotic volume decrease.

IG20 (MADD splice variant - 5), a proapoptotic protein, interacts with DR4 / DR5 and enhances TRAIL - induced apoptosis by increasing recruitment of FADD and caspase - 8 to the DISC.

Replication increases β - cell vulnerability to human islet amyloid polypeptide - induced apoptosis

That's how the tumor cells may be able to avoid the induced apoptosis,» says Zou.

As a result, the animals treated with blueberry, spinach, or spirulina were reported to have reduced ischemia / reperfusion - induced apoptosis and cerebral infraction.

Cucurmosin has been shown to induce apoptosis in various cancer cells tested.

Goji's are reported to have anti-aging properties and show anti-tumor activities against various types of skin cancer cells by inhibiting tumor growth and inducing apoptosis.

Rather, the group speculates that the transplanted cells secreted protective neurotrophins, proteins that promote cell survival by keeping neurons from inducing apoptosis (programmed cell death).

In patients with ALL, this leads to a sharp fall in serum levels of asparagine, hindering protein synthesis in malignant cells and inducing apoptosis, or programmed cell death.»

So alpha - lac may induce apoptosis by directly causing the destruction of DNA from within the cell's nucleus, or it may instigate the suicide - generating caspace cascade through the mitochondria.

Certain existing chemotherapy drugs are designed to induce apoptosis, rather than «septic» cell death which is called necrosis, for this reason.

Activation of the Fas receptor then induces apoptosis in these cells.

By contrast, DN T cells are able to mediate DTH to donor alloantigens and induce apoptosis of donor - specific corneal endothelial cells.

The capacity of each cell population to induce apoptosis was tested using a 24 - hr three - color apoptosis assay.

The role of DN T cells in corneal allograft rejection was confirmed in two separate in vitro assays in which CD8 − cells were isolated from CD4 KO donors that had rejected corneal allografts and were found to induce apoptosis of donor - specific corneal cells.

miR - 34a suppresses proliferation and induces apoptosis of human lens epithelial cells by targeting E2F3.

In addition, consistent with past studies, AAV2 - infected cancer cells produced more Ki - 67, an immunity system activating protein and c - Myc, a protein that helps both to increase cell growth and induce apoptosis.