Sentences with phrase «induced gene silencing»

Graduate student André Velásquez from Greg Martin's lab shows how to do Virus - induced Gene Silencing (VIGS) in Nicotiana benthamiana and Tomato.

Not exact matches

Significant binding by miR -124-3p to two of the potential target genes was seen, as measured from immunoprecipitated RNA - induced silencing complexes.

Gore and her colleagues believe these effects are epigenetic; that is, rather than inducing genetic mutations, which would change the sequence of the rats» DNA, the fungicide is permanently silencing or reprogramming normal genes that control development and behavior.

In other work, the lab is exploring the mechanisms of heterochromatin formation and gene silencing through the study of a protein complex called RNA - induced initiation of transcriptional gene silencing (RITS).

These results suggest that inhibition of mTOR - raptor complex or silencing mTOR gene expression induced cell cycle arrest at G1 phase in ALK + ALCL cells.

We also show that inhibition of mTOR with rapamycin, as well as silencing mTOR gene product expression using mTOR - specific small interfering RNA, decreased phosphorylation of mTOR signaling proteins and induced cell cycle arrest and apoptosis in ALK + ALCL cells.

siRNA has already been shown to be an efficient tool for silencing genes in cells, but previous attempts have produced chemically modified siRNA lasting only 15 - 45 minutes in the body and often inducing undesired immune responses.

Aquarius is required to initiate small - RNA - induced heritable gene silencing.

Small RNAs play a crucial role in genome defense against transposable elements and guide Argonaute proteins to nascent RNA transcripts to induce co-transcriptional gene silencing.

1) Plant - mediated gene silencing: Using plant - mediated gene silencing, scientists induce plants to transfer pieces of genetic material to other organisms, targeting and interfering with the interactions between plants and their pests at the genetic level.