Inhibit key enzymes in cancer cell specific metabolic pathways to disrupt tumor cell proliferation and survival
Glyphosate
inhibits a key enzyme that plants use to make amino acids.
Research shows that turmeric
inhibits a key enzyme (elastase) that reduces the ability of elastin from forming.
Not exact matches
UJI researcher Florenci González Adelantado explains how they work: «The new chemical compounds
inhibit the action of the
enzymes that catalyse
key metabolic processes during the infection by the parasitic protozoas that cause infectious tropical diseases.
Though it's unclear what effect, if any, BPA may have on egg quality during IVF, «there is mounting data that a
key enzyme that helps convert testosterone to estrogen may be
inhibited by BPA,» said Bloom.
The Surolias went on to show that, like in bacteria, triclosan is the wrench that jams Plasmodium's fatty acid machinery; it
inhibits one of the
key enzymes in the biochemical conveyor belt.
In a new study, researchers demonstrate that the
enzyme FIH (Factor
Inhibiting HIF) is a
key to how this switch - over happens.
Hancock's group showed that
inhibiting the
enzyme p300 can affect the functions of another protein, Foxp3, which plays a
key role in controlling the biology of Tregs.
Statins
inhibit the
enzyme HMG - CoA reductase, one of the MVP's
key components.
Their compound, which is intended to repair brain damage that has already occurred, is a significant departure from current Alzheimer's treatments, which either slow the process of cell death or
inhibit cholinesterase, an
enzyme believed to break down a
key neurotransmitter involved in learning and memory development.
«It
inhibits tyrosinase, which is the
key enzyme in pigment production, through its interaction with copper,» helping skin look brighter.
This complex synthesis involves 37 steps and starts with a
key enzyme known as HMG - CoA reductase (
inhibited by statins, a class of cholesterol - lowering drugs).
DHEA and its metabolite etiocholanolone (also reported by the 24 - Hour Urine Test, see below),
inhibit glucose -6-phosphate dehydrogenase (G6PD), an
enzyme that plays a
key role in anerobic glycolysis, the major route of energy production for cancer cells.91, 92
They also may
inhibit leptin, a hormone made by adipose cells which
inhibits hunger and this dysregulation may be one of the ways that feeding infant formula encourages obesity and weight gain in infants and later in life.59 • Protease inhibitors are substances that inactivate some
key digestive
enzymes like trypsin and chymotrypsin and are associated with pancreatitis and pancreatic enlargement.
Making matters even worse, mercury
inhibits the activities of glutathione reductase and glutathione synthease, the two
key enzymes critical to glutathione metabolism, and interferes with the function of superoxide dismutase, another
enzyme needed by the body for antioxidation.34 - 37
It's been shown to
inhibit the
enzyme lysinase, which breaks down lysine, one of the
key amino acids in collagen, but only in an oral study.
Statins such as Lipitor, Zocor, Pavacol and Mevacor lower cholesterol by
inhibiting HMG - CoA reductase, a
key enzyme in cholesterol synthesis.