Inhibition of adhesion of uropathogenic Escherichia coli bacteria to uroepithelial cells by extracts from cranberry.
Not exact matches
«Virtual tissue technology reveals new drug target in polycystic kidney disease: Advanced computer simulations show that failures
of cell
adhesion and
inhibition cause two types
of kidney cyst formation.»
Cells can fail to stick together sufficiently, referred to as reduced cell
adhesion, or they can stick together normally but not respond in the correct way to that contact, referred to as a loss
of contact
inhibition.
In contrast, loss
of adhesion induced the phosphatases Dusp4 and -5 (Map - kinase phosphatases), which are inhibitors
of the MAP - kinase signaling pathway, whereas contact
inhibition induced the quiescent cell - specific transcription inhibitor E2F4.
Photographs
of growing cells (A), and cells arrested overnight by loss
of adhesion (B), contact
inhibition (C), or mitogen withdrawal (D) are shown.
While the mechanisms
of action
of cranberry products on bacterial
adhesion and biofilm formation are not fully understood, this research demonstrates that cranberry juice is better for the
inhibition of biofilm formation than PACs or isolated A-type cranberry flavonoids.
Inhibition of Helicobacter pylori
adhesion to human gastric mucus by a high - molecular - weight constituent
of cranberry juice.
Shortening
of soft - tissues,
adhesions and
inhibition in movement is increased dependent upon %
of tension (vs. current capacity), restricted range
of motion movements coupled with current mobility limitations.