Sentences with phrase «innate immunity adaptive»

Innate Immunity Adaptive Immunity Infection and Immunity Vaccination Clinical Immunology & Allergy Mucosal Immunology Microbiome and Immune Response Comparative Immunology Immunity and Nutrition Immunogenetics

Not exact matches

Sian says: «As well the part of our immune system known as «innate immunity», the body also has processes in place called «adaptive immunity» which is when the body recognises a virus it has encountered before and initiates a response.

Focusing on basic research for the functional regulation of innate and adaptive immunity and on translational research for cancer immunotherapies, the National Key Laboratory of Medical Immunology has been conducting innovative research and exploration, and is becoming a rising star in the international immunology community.

«Our multi-ethnic exploration of innate and adaptive immunity highlights a remarkable level of sharing across human populations of genetic variation influencing immune function, while identifying interesting instances of genetic effects on immune function that are specific to a population,» said Nir Hacohen, PhD, MGH and the Broad Institute, study author.

«Single dose Ebola vaccine is safe, effective in monkeys against outbreak strain: VSV - EBOV appears to trigger innate, adaptive immunity.»

As with innate immunity, the adaptive immune system — the T cells and antibodies produced by B cells that target specific molecules on invading cells — contributes to pathology or may also fight against it.

Areas covered range from basic studies into the biology of innate and adaptive immunity (immune cell development and differentiation, immunogenomics, systems immunology, structural immunology, antigen presentation, immunometabolism, and mucosal immunology) to immune contributions to health and disease (host defense, inflammation, cancer immunology, autoimmunity, allergy, transplantation, and immunodeficiency).

All plants and animals have a built - in resistance to pathogens called innate immunity that is more basic and general than the better - known adaptive immunity that responds to specific infections or vaccines.

«We had this really good lymph - node - targeting vaccine that will drive very strong adaptive immunity, and they had this combination that was recruiting innate immunity very efficiently,» Irvine says.

The vertebrate immune system has two parts: innate and adaptive immunity.

In addition, this collaborative effort has allowed the establishment of a large biological specimen repository that supports research in virology, adaptive, and innate immunity.

In his current position, he studies the role of interferon - regulatory factors in the regulation of innate and adaptive immunity, in collaboration with Tadatsugu Taniguchi.

With respect to biological applications, the group is focusing on how cellular heterogeneity and cell - to - cell communication drive ensemble - level decision - making in the immune system, with an emphasis on «two - body» interaction (e.g., host cell - virus interactions, innate immune control of adaptive immunity, tumor infiltration by immune cells).

By showing that ligands associated with innate immunity enable dendritic cells to initiate T cell responses, this work provided the key missing link between the innate and adaptive immune responses.

Viruses that escape this checkpoint drain through lymph vessels to local lymph nodes, where it was assumed macrophages finished the job of the innate immune system before specialized adaptive immunity kicked in.

The main mechanism includes phagocytosis of macrophages which play a critical role in nonspecific defense (innate immunity) and, moreover; they have a role as antigen presenters which also help initiate specific defense mechanisms (adaptive immunity) by recruiting other immune cells such as lymphocytes.

The mucosal lining of the female genital tract differs from that of the gastrointestinal tract in terms of cellular composition, microflora, and effector mechanisms of innate and adaptive immunity, although it should be noted that the immunologic anatomy and biology of the genital, anal, and lower rectal tract mucosae are less well defined than those of the remainder of the gastrointestinal tract.

The range of subjects includes, but is not limited to, immune cell development and senescence, signal transduction, gene regulation, innate and adaptive immunity, autoimmunity, infectious disease, allergy and asthma, transplantation, and tumor immunology.

Uncovering the roles that innate and adaptive immunity play during these infectious processes are key research questions in the Coler lab.

Here, we hypothesize that failures in innate immunity observed in frail elderly are related to those alterations described in adaptive immunity defined as the IRP.

Among the diversity of immune cell types, dendritic cells (DCs) are central to the immune response and have the unique capacity to link innate and adaptive immunity.

In order to prevent autoimmunity and «collateral damage» to host tissues in the course of responses to pathogens, innate and adaptive immunity are subject to stringent control mechanisms.

Arcus Biosciences is an oncology company researching adaptive immunity and innate immunity to discover drugs with broad applicability in combination therapies.

Besides their well - known function as effector cells in allergic responses, mast cells were reported to play a critical role in innate immunity and to exert important stimulatory but also suppressive functions in adaptive immune responses.

Interleukin 15 (IL - 15) regulates the development, survival, and functions of multiple innate and adaptive immune cells and plays a dual role in promoting both tumor cell growth and antitumor immunity.

The macrophages release cytokines that can activate more innate immune cells, readying them for attack on viruses or cancer cells, or they can activate the adaptive arm of immunity, priming it for clonal expansion.

Both your innate and adaptive immunity needs proper tools to fight off invaders that can make you uncomfortable and sick.

One is as a regulatory hormone in inflammation and both innate and adaptive immunity.