Sentences with phrase «innate immune activity»
Olesen R, Vigano S, Rasmussen T, Søgaard OS, Ouyang Z, Buzon M, Bashirova A, Carrington M, Palmer S, Brinkmann CR, Yu XG, Østergaard L, Tolstrup M, Lichterfeld M. Innate immune activity correlates with CD4 T cell - associated HIV - 1 DNA decline during latency - reversing treatment with panobinostat.
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Our experts in mucosal vaccine delivery have established in vitro and in vivo models to assess the activity of adjuvants and vaccine formulations on innate and adaptive immune cells, as well their capacity to stimulate different effector mechanisms of clearance.
Specifically, inflammatory cells of the innate immune system have been shown definitively to have tumor - promoting activity.
This team plans to conduct the first human clinical trial combining these two therapeutic strategies (which have been tested separately and have shown activity in reducing HIV in humans), with the expectation that a boosted innate immune system empowered with unique antibodies to target HIV - infected cells will achieve greater reductions in HIV than observe previously.
Interferon signaling is central to the innate immune system, so answers to these questions also can lead to better understanding of cancers and diseases and new drugs related to immune activity or malfunction.
Finally, we are delineating the innate immune signaling pathways governing the antiviral restriction activities of the protein SAMHD1.
The factory workers had increased activity of NK cells (the white blood cells that seek and destroy pathogens as part of your innate immune response), higher levels of the important mucosal antibody secretory IgA (sIgA) and lower levels of pro-inflammatory immune complexes when compared to office workers.
Its novel mode of action specifically targets and inhibits the cytokines involved in itch and inflammation with minimal activity against cytokines involved in hematopoiesis or innate immune function.
Greater scores on the first principle component (PC1) were inversely associated with CD56 (Natural Killer Cells) and positively associated with CD4 (T helper cells) and CD19 (B or T helper cells), suggesting a relationship to both innate and acquired immune system activity.