Ca2 + puffs originate from preestablished stable clusters of
inositol trisphosphate receptors.
Inhibition of thromboxane A2 - induced arrhythmias and intracellular calcium changes in cardiac myocytes by blockade of
the inositol trisphosphate pathway.
With this new understanding of the enzyme, called
Inositol trisphosphate 3 - kinase B (ItpkB), scientists are closer to improving therapies for diseases such as bone marrow failure syndrome, anemia, leukemia, lymphoma and immunodeficiencies.
Not exact matches
Chlamydia trachomatis inclusion showing recruitment of the
inositol 1,4,5 -
trisphosphate receptor type 3 to microdomains on the inclusion membrane (red).
JPET 2010, 333 (3), 726 - 735 Conventionally, G protein - coupled receptors are thought to increase calcium via
inositol 1,4,5 -
trisphosphate (InsP (3)-RRB-.
Regulation of
inositol 1, 4, 5 -
trisphosphate receptor - mediated calcium release by the Na / K - ATPase in cultured renal epithelial cells.
Dr. Snyder applied receptor techniques to elucidate intracellular messenger systems including isolation of
inositol 1,4,5, -
trisphosphate receptors and elucidation of
inositol pyrophosphates as phosphorylating agents.
University of Oxford, 2008 Traditionally oxytocin is believed to regulate uterine contractility by releasing Ca2 + via
inositol 1, 4, 5 -
trisphosphate (IP3).
Stimulation of the TCR results in cleavage of phosphatidylinositol 4,5 - bisphosphate to form
inositol 1,4,5 -
trisphosphate, which induces intracellular calcium flux, and DAG, which binds to RasGRP1 and PKC - θ to contribute to activation of these proteins (28).
Sub-second oscillations of
inositol 1,4,5 -
trisphosphate and
inositol 1,3,4,5 - tetrakisphosphate during platelet activation by ADP and thrombin: lack of correlation with calcium kinetics