Interactions of coffee consumption and postmenopausal hormone use in relation to breast cancer risk in UK Biobank, Cancer Causes and Control, published online.
Not exact matches
We tested the proportional - hazards assumption by modeling the
interaction of follow - up time with
coffee consumption and observed no significant deviations.
Although the gene ×
coffee interaction did not reach significance in either group, the modifying effect
of CYP1A2 genotype on risk
of MI associated with
coffee consumption was similar for both smokers and nonsmokers (Table 3).
It is well known that the half - life
of caffeine is reduced by 30 % to 50 % in smokers and doubled in women taking oral contraceptives or other exogenous forms
of estrogen.19 Therefore, we tested the
interactions between these factors and caffeine or
coffee consumption for depression risk.