Tests failed to pin the outbreak, which has since waned, on common
pig viruses.
That and PERVs —
those pig viruses — sunk those efforts; xeno was dead in the water for 15 years.
When given to ferrets, it produces a disease whose symptoms are all but identical to the Iowan
pig virus.
Again the question is, it's not
a pig virus because we are not seeing it circulating in pigs.
After a flood of optimism and investment in the early 1990's, the struggle to overcome host immune response and fears that organs could transmit
pig viruses to humans scared off pharmaceutical funders.
Tests confirmed that five pigs have pseudorabies,
a pig virus that agriculture officials aggressively try to keep out of commercial herds.
Essentially, the problem with the vaccine is that
a pig virus has been found to contaminate the vaccine.
Not exact matches
I do n`t like calling Rush
Pig, a
Pig is much better Animal then him I think he is just
Virus.
Find out whether the H1N1 or swine flu
virus can be transmitted through pork and whether
pigs spread swine flu to people or peo...
The next pandemic
virus may be circulating on U.S.
pig farms, but health officials are struggling to see past the front gate
In other words, the big
pig centers in the midwestern parts of the country become pools of various strains of the
virus, giving it more opportunities to swap genes and potentially turn into more harmful, more easily transmitted varieties that could go pandemic in people.
Nelson and her colleagues created animations that show the spread of the
virus among traveling
pigs.
«Understanding the importance of long - distance
pig transportation in the evolution and spatial dissemination of the influenza
virus in swine may inform future strategies for the surveillance and control of influenza,» Nelson and her colleagues concluded in their paper.
Nelson and her colleagues found that flu in
pigs «follows long - distance swine movements from the southern U.S. to the Midwest,» with most of the human - origin H1N1 arriving at Midwest hog farms coming from the Southeast, and most of the swine - origin H1N2 coming from the south - central U.S. And that means the Midwest, as the final destination for many of these
pigs, is «likely to provide a reservoir for multiple genetically distinct variants to co-circulate and exchange segments via re-assortment because of the continual importation of swine influenza
viruses from other regions,» the researchers noted.
The study adds to evidence that keeping an eye on bat
viruses could reduce future viral outbreaks — in
pigs and humans.
The new flu, which has elements of
pig, bird and human flu
viruses in it, has been circulating for at least a month in Mexico.
To take the pulse of
pig flu, we spoke with Chris Olsen, a professor of public health and head of the Olsen Laboratory, which studies influenza A
viruses, at the University of Wisconsin — Madison School of Veterinary Medicine.
In the winter of 2009, people living near a giant industrial
pig farm in La Gloria, Mexico, reportedly became ill with a severe respiratory
virus.
The emergence of the new H1N1 flu strain has demonstrated the effectiveness of existing systems to watch for human flu outbreaks while also proving a long - standing theory that
pigs could serve as mixing vessels for a pandemic
virus.
Benzoquinoline was also effective against vesicular stomatitis
virus from the rhabdovirus family, which can infect insects, cattle, horses and
pigs, and Zika
virus, which is spread to humans by mosquitoes.
After 1919, the descendants of the H1N1
virus continue to circulate and cause seasonal flu outbreaks in humans — and
pigs.
It is a hybrid of human, bird and swine flu
viruses, and by 1999 it is the dominant flu strain in US
pigs.
US
pig farms try to control it with vaccines, but these attempts are largely ineffective because the
virus evolves too rapidly, changing the surface proteins targeted by the vaccine while keeping its internal genes unchanged.
«We are keeping birds and
pigs in numbers that are unprecedented, so you create new niches for animals, and especially for
viruses to emerge.»
An H1N1
virus jumps from
pigs to humans and kills a US army recruit.
The two strains had a common H1N1 - type ancestor, but both have been evolving independently in
pig populations, and the minute changes to viral genes that allowed the
virus to adapt to a new host were different in each strain.
He thinks surveillance of an entire rural ecosystem —
pigs, birds, people, as well as dogs, cats, horses, and other domesticated and wild animals — would finally yield some deeper insights into why and how flu
viruses evolve.
Fortunately, Nipah
virus in Malaysia did not appear to be transmitted between people, and the culling of
pigs greatly reduced the odds of transmission from
pig to human.
In the new study, the researchers exposed
pigs to the H7N9
virus.
Erasing potentially dangerous
viruses brings field a step closer to making up organ shortage with
pig parts
Yet
pigs are a likely source of a human pandemic H5N1
virus because they are susceptible to both human and avian
viruses, creating opportunities for genetic reassortment in co-infected animals.
Genomic RNA editing and its impact on Ebola
virus adaptation during serial passages in cell culture and infection of guinea
pigs
McIntosh says there are still a lot of unknowns, including how the
virus was transmitted to the
pigs and whether they show any symptoms independent of blue ear disease.
This means the
virus could still be spreading and evolving because the team discovered, to their surprise, that infected
pigs show no symptoms.
Sometimes, in the gene shuffling with
viruses in birds and
pigs, the changes are so great that the flavor changes completely.
His team also confirmed
pig - to - human Ebola transmission by identifying six
pig handlers, whose blood tested positive for antibodies to the
virus, although they showed no symptoms.
Nidom says that in one
pig, the
virus had developed the ability to bind to a molecule present in the noses of both
pigs and humans.
However, they identified genetic sequences matching
viruses that infect dogs, chickens, and
pigs, suggesting the possibility that some of the
viruses had crossed over from other species.
Chairul Nidom of Airlangga University in Surabaya, Indonesia, and colleagues in Japan, have been tracking H5N1 in
pigs since 2005 in Indonesia, the country hardest hit by the avian flu
virus.
The most recent pandemic occurred in 2009, with the appearance of the «swine flu,» so named because the
virus was first found in
pigs.
«H5N1
viruses could easily evade detection as they spread through Indonesia in asymptomatic
pigs,» warn Nidom and colleagues.
He worries that the
virus's passage through
pigs could allow it to mutate into something more harmful.
«If the
virus was better adapted to
pigs it would have spread like wildfire,» says Ab Osterhaus of the University of Rotterdam in the Netherlands, a flu expert not involved in the research.
They believe a vaccine that stimulates the body to produce more of these cells could be effective at preventing flu
viruses, including new strains that cross into humans from birds and
pigs, from causing serious disease.
In each case, the
virus in
pigs closely resembled H5N1 from nearby outbreaks in poultry, suggesting it has jumped from the bird to the
pig population.
If you remember, too, that H1N1 is originally a human
virus, it was given to
pigs by us, and it still circulates, a different variant of it obviously, still circulates in people.
One of the lessons was that there may be a fair amount of cross-protective immunity in the human population to a number of the
viruses currently circulating in swine, some of which were introduced into
pigs from people in the past.
A new variant of an influenza
virus that circulates in
pigs has been jumping occasionally into people, providing a surprisingly early opportunity for public health officials to test out some of the lessons learned from the 2009 H1N1 pandemic.
Sales of pork plunged in 2009 when the new H1N1 was identified as swine flu, a reference to the fact it was comprised mainly of genes from flu
viruses that circulate in
pigs.