Sentences with phrase «ipilimumab effects»
«Adjuvant Ipilimumab effects survival after high risk lymph node and melanoma resection.»
https://www.sciencedaily.com/ Not exact matches
Indeed, the authors point out that Ipilimumab might better effect recurrence - free survival than adjuvant interferon and should be considered as an option by oncologists in this field considering its activity across subgroups including those with high tumor burden.
In addition, combining the anti-RANKL antibody with ipilimumab produced a synergistic effect and helped prolong survival.
Patients in the clinical trial who got the combined therapies also had fewer serious adverse side effects than those who received only ipilimumab, the researchers report in the Journal of the American Medical Association.
Hodi designed this investigator - initiated clinical trial to find out if giving sargramostim along with ipilimumab would have a synergistic effect against the melanoma — like pressing the immune system's accelerator while releasing the brake.
They studied the effects of this treatment in combination with ipilimumab, a U.S. Food and Drug Administration - approved immunotherapy.
«But this opens the possibility of improving clinical outcomes and decreasing serious side effects in treating advanced melanoma with ipilimumab.»
«Combined checkpoint inhibitor treatments, such as ipilimumab - nivolumab, have produced higher response rates, but they can have serious side effects.
A second study — from the Institut Gustave Roussy in Paris, published in the same issue of Science — found that antibiotics could disrupt the antitumor effects of ipilimumab.
«The side effects were quite high with the combination, with about 30 % of patients discontinuing due to treatment - related adverse events, as compared to 5 % with nivolumab and 13 % for ipilimumab.»
Advanced melanoma patients successfully treated with a combination of nivolumab and ipilimumab may endure severe side effects, but they do not suffer any clinically meaningful changes in health - related quality of life.