Not exact matches
This clinical study, published
in the Proceedings of the National Academy of Sciences, tested the possibility of imaging inflammation
in the pancreas of human volunteers using ferumoxytol, a coated
iron nanoparticle approved by the FDA as an
iron replacement therapy, and MRI.
«Neodymium
iron boron
nanoparticles are difficult to make because they are very reactive,» Hadjipanayis says,
in addition to being hard to align within a given nanostructure.
One species, Magnetospirillum gryphiswaldense, is easily cultivated
in the lab — with or without magnetic
nanoparticles in their interior depending on the presence or absence of
iron in the local environment.
Mitragotri reckons that the particles could provide a way to get drugs into the body at a more constant concentration, or substances such as
iron oxide
nanoparticles, which increase contrast
in magnetic resonance imaging.
In other words, they could tell the extent to which an individual
nanoparticle of lithium
iron phosphate had reacted.
The firm's most ambitious effort to peer inside us will use
iron nanoparticles that attach to specific molecules
in the bloodstream linked to cancer or heart disease.
An
iron oxide
nanoparticle applied to teeth prior to treatment with hydrogen peroxide effectively reduced the onset and severity of cavities (indicated with red arrows)
in rats.
Yet, to be effective, the size of the
iron oxide
nanoparticles had to be just right — and had to be maintained
in a strong matrix that was both flexible and resilient to deal with large volume changes while optimally conducting electricity.
Gao and Koo reached out to Cormode, who had experience working with
iron oxide
nanoparticles in a radiological imaging context, to help them synthesize, characterize and test the effectiveness of the
nanoparticles, several forms of which are already FDA - approved for imaging
in humans.
In that study, Gao showed that an
iron oxide
nanoparticle behaved similarly to a peroxidase, an enzyme found naturally that catalyzes oxidative reactions, often using hydrogen peroxide.
An intensive collaboration between University of Helsinki, Finland, and Okinawa Institute of Science and Technology, Japan, showed that
in some condition
iron nanoparticles can grow
in cubic shape.
To create the spermbots, the team made microtubes 50 microns long, by 5 to 8 microns
in diameter from
iron and titanium
nanoparticles.
A combination of
iron - oxide
nanoparticles and an alternating magnetic field, which together generate heat, have activated an immune system response to tumors
in mice according to an accepted manuscript by Dartmouth - Hitchcock Norris Cotton Center researchers
in the journal Nanomedicine: Nanotechnology, Biology and Medicine released online on February 24, 2014.
An endowed professor of pediatric cardiology at Children's Hospital of Philadelphia
in Pennsylvania, Levy had been working with his team on biodegradable polymer
nanoparticles infused with
iron oxide.
Previously, the IBS team designed ultrasmall T1
iron oxide
nanoparticles (PEG - IONCs), proved the possibility to synthesize them
in large quantities, and tested them on mice.
Researchers at Umeå University, together with researchers at Uppsala University and Stockholm University, show
in a new study how nitrogen doped graphene can be rolled into perfect Archimedean nano scrolls by adhering magnetic
iron oxide
nanoparticles on the surface of the graphene sheets.
By this method they obtain anchoring sites for the
iron oxide
nanoparticles that are decorated onto the graphene sheets
in a solution process.
HYEON Taeghwan, director of the Center for
Nanoparticle Research explains: «Let's take the example of a MRI analysis of a brain with Alzheimer's:
iron oxide
in the blood vessels would appear as black and the amyloid plaques as gray.
In place of gadolinium - based contrast agents, the researchers have found that they can produce similar MRI contrast with tiny
nanoparticles of
iron oxide that have been treated with a zwitterion coating.
Before injecting nematodes with magnetic
nanoparticles, the scientists first coated the manganese —
iron nanoparticles with polyethylene glycol, a molecule that targeted the particles to the mucus layer of the amphid region (an opening near the nematode's mouth that hosts the nerve cells involved
in the heat avoidance reflex).
When the scientists examined the cells
in the growing communities closely, they found
nanoparticles of magnetite on the surface of cells and,
in some cases, grains of the
iron mineral connecting microbial pairs.
To get round this, Wilhelm Roell at the University of Bonn
in Germany and his colleagues loaded muscle stem cells with
iron oxide
nanoparticles to make them magnetic.
The team used
iron oxide for the core of the
nanoparticles, which not only enables the team to use them for magnetic resonance imaging, but opens up possibilities
in remote guidance and localized magnetic heating to hasten the breaking up of the clots.
Identification of the precise 3 - D coordinates of
iron, shown
in red, and platinum atoms
in an
iron - platinum
nanoparticle..
The image of the
iron - platinum
nanoparticle (referenced
in the headline) reminds of foetal ultrasound images.
By taking multiple images of the
iron - platinum
nanoparticle with an advanced electron microscope at Lawrence Berkeley National Laboratory and using powerful reconstruction algorithms developed at UCLA, the researchers determined the precise three - dimensional arrangement of atoms
in the
nanoparticle.
Now, UCLA [University of California at Los Angeles] physicists and collaborators have mapped the coordinates of more than 23,000 individual atoms
in a tiny
iron - platinum
nanoparticle to reveal the material's defects.
The Bulte Lab has developed methods to label cells magnetically using tiny superparamagnetic
iron oxide
nanoparticles in order to make them visible by magnetic resonance imaging; this technology has now been introduced
in the clinic for several cell therapy applications.
«Deficient neuron - microglia signaling results
in impaired functional brain connectivity and social behavior» Y. Zhan, R.C. Paolicelli, F. Sforazzini, L. Weinhard, G. Bolasco, F. Pagani, A. L. Vyssotski, A. Bifone, A. Gozzi, D. Ragozzino, C.T. Gross Nature Neuroscience 17 (3), 400-4006 (2014) «USPIO - loaded Red Blood Cells as a biomimetic MR contrast agent: a relaxometric study» A. Boni, D. Ceratti, A. Antonelli, C. Sfara, M. Magnani, E. Manuali, S. Salamida, A. Gozzi, and A. Bifone Contrast Media and Molecular Imaging 9, 229 - 236 (2014) «Distributed BOLD and CBV - weighted resting - state networks
in the mouse brain» F. Sforazzini, A.J. Schwarz, A. Galbusera, A. Bifone, and A. Gozzi NeuroImage 87, 403 - 415 (2014) «Antimicrobial peptides design by evolutionary multiobject optimization» G. Maccari, M. Di Luca, R. Nifosì, F. Caldarelli, G. Signore, C. Boccardi, and A. Bifone PloS Computational Biology 9 (9): e1003212 (2013) «Differential effect of orexin - 1 and crf - 1 antagonism on stress circuits: a fMRI study
in the rat with the pharmacological stressor yohimbine» A. Gozzi, S: Lepore, E: Merlo Pich, and A. Bifone Neuropsychopharmacology 38 (11): 2120 - 2130 (2013) «Water dispersal and functionalization of hydrophobic
iron oxide
nanoparticles with lipid - modified poly (amidoamine) dendrimers» A. Boni, L. Albertazzi, C. Innocenti, M. Gemmi, and A. Bifone.
Previously, the Institute for Basic Science (IBS) team designed ultra-small T1
iron oxide
nanoparticles (PEG - IONCs), proving the possibility to synthesise them
in large quantities.
A 2017 study co-authored by John Bischof, professor of mechanical engineering at the University of Minnesota, and published
in Science Translational Medicine, used specially coated
iron oxide
nanoparticles.
Napier's presentation, titled «Superparamagnetic
Iron Oxide
Nanoparticles for Delivery of DNA - based Contraceptive Vaccines for Feral Cats,» dealt with a portion of Napier's research
in developing and delivering contraceptives to feral cats.
As worrying, Planktos boasts on their website that the
iron they dump will be
in nanoparticle form because
nanoparticles float longer than normal particles.