Subjects were participants in the Women's
Ischemia Syndrome Evaluation (WISE) who had reported chest pain and were thus suspected to suffer from myocardial ischemia (defined as pathological loss of or reduction in blood flow — ischemia — to a part of the muscular tissue of the heart — myocardium).
Chronic inflammation has been noted as the culprit for multiple diseases and conditions such as Alzheimer's disease (AD), Parkinson's disease, multiple sclerosis, epilepsy, cerebral injury, cardiovascular disease, metabolic
syndrome, cancer, allergy, asthma, bronchitis, colitis, arthritis, renal
ischemia, psoriasis, diabetes, obesity, depression, fatigue (2)