They determined which of these SNPs are different in TEDDY participants who had developed type 1 diabetes versus those who had
Islet cell autoantibodies versus those who still had neither.
In fact, while
Islet cell autoantibodies, or IA, are considered a red flag for type 1 diabetes, not every child with IA will progress to full - blown disease, She says, although multiple autoantibodies definitely increase that risk.
Not exact matches
* In type 1 diabetes, the insulin - producing
cells in the Langerhans
islets of the pancreas are destroyed because they are attacked by the body's immune system (formation of
islet autoantibodies against structures of the beta
cells).
Currently, the best approach for predicting those at risk for developing T1DM before symptoms appear is by measuring
autoantibodies to
islet cell antigens in the pancreas.
These include genetic markers,
autoantibodies against
islet beta
cells, and T
cells responses to beta
cell antigens.
The Risk of
Islet Cell and Insulin
Autoantibodies and Their Predictive Strength as Markers of Type - 1 Diabetes in a Cross-Section of Nigerian Population