In a paper published earlier this year in Molecular Cell, he and his team explored the activity of the FOS /
JUN protein complex, which is expressed across many different cell types in the brain but appears to regulate unique programs in each different cell type.
He was able to show that the leucine repeats on c -
jun and c - fos «zipped» the
proteins together — evidence that C - FOS
proteins could interact with other
proteins involved in cancerous cell replication.