Sentences with phrase «kd mice»

An additional cohort of DAT KD mice was trained on a visual attention task, and no deficits were observed, confirming that the changes in timed behavior were not attentionally mediated.

Our data indicates that human htt ameliorates the cognitive deficits observed in the KD mice.

Not exact matches

In their current PNAS paper, the multidisciplinary team of Rodó, Burns, Dan Cayan, PhD, a climate researcher at UC San Diego Scripps Institution of Oceanography and co-authors in New York, Barcelona and Japan, say the new evidence suggests that the most likely cause of KD is a «preformed toxin or environmental molecule» originating from northeastern China, possibly related to Candida, which has been linked to Kawasaki - like coronary artery vasculitis in mouse models.

Subramanian S, Goodspeed L, Wang S, Kim J, Zeng L, Ioannou GN, Haigh WG, Yeh MM, Kowdley KV, O'Brien KD, Pennathur S, Chait A. Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor - deficient mice.

In order to better understand the liabilities associated with reducing normal htt in adult mice, we evaluated the effects of a robust knock down of WT htt both in CNS and periphery in a conditional htt knock - down (KD) model induced by doxycycline.

Administration of raclopride (0.2, 0.6, and 1.2 mg / kg), a D2 antagonist, obliterated most of the differences between DAT KD and WT mice, suggesting that the effects of chronically elevated dopamine levels on interval timing were mediated by the D2 receptor sub-type.

Finally, to determine whether LARP7 KD also results in an increase in breast cancer metastasis in vivo, the T47D control or shLARP7 - 2 cells were injected intravenously into the nude mice, and lung metastasis was examined 12 weeks later.

When administered in restricted amounts, which do not exceed the individual's total energy needs, the KD can also be therapeutic against malignant brain tumors in mice and humans.

In the mouse model of multiple sclerosis (MS), a positive effect of modified fasting and ketogenic nutrition (KD) on disease development and clinical course has been shown in several studies.

A recently published study found that a long - term KD caused glucose intolerance (in mice).

During the past years, a multitude of mouse studies indeed proved anti-tumor effects of KDs for various tumor types, and a few case reports and pre-clinical studies obtained promising results in cancer patients as well.

KD [Ketogenic Dieting by healthy mice]....