Sentences with phrase «kkay obese mice»

In a study published in the journal Food Chemistry in 2014, a team of researchers analyzed how the bioactive compounds of seven different varieties of apples - Granny Smith, Braeburn, Fuji, Gala, Golden Delicious, McIntosh and Red Delicious - affected the good gut bacteria of diet - induced obese mice.

«How obesity dulls the sense of taste: Obese mice had about 25 percent fewer taste buds than lean mice in study.»

Handa, T., Yamaguchi, K., Sono, Y., and Yazawa, K. Effects of fenugreek seed extract in obese mice fed a high - fat diet.

Friedman's group was able to track down the mutation in the obese mice and found that it blocked production of a particular protein hormone, which they named leptin.

In the case of the obese mice, Sinclair observes, resveratrol increased insulin levels while decreasing glucose levels, resulting in healthier liver and heart tissue when compared with obese mice that did not receive treatment.

Two weeks after the transfer, recipient mice had lost considerable weight; another group that received microbes from obese mice in a placebo group — undergoing surgery without gastric bypass — stayed the same.

Scientists reached this conclusion by transferring microbes from bypass - treated obese mice to a group of lean mice raised in sterile conditions that left them with no intestinal bacteria at all.

Chen tested Nobiletin on obese mice with and without a functional clock.

The large amounts of fat around the testes of obese mice, «could alter the environment and encourage epigenetic changes», says Teague, who presented the results at the 14th World Congress on Human Reproduction in Melbourne, Australia, this month.

Like the obese mice, the children were constitutionally unable to produce the appetite - regulating hormone.

When tumor cells that no longer express CCR3 are implanted in the prostates of mice, tumor progression and dissemination are significantly reduced, especially in obese mice.

A drug that reverses the condition in obese mice could make it much easier to control the disease

Carrying excess fat does not contribute to a warmer body in obese mice, a new study on the insulating effects of fat finds.

The mice that received the microbiomes of the obese mice gained significantly more weight than did the mice with the lean - mouse microbiomes.

Back then, Harrison restricted calories for genetically modified obese mice, which remained extremely fat even when food was cut.

«The nondigestible compounds in the Granny Smith apples actually changed the proportions of fecal bacteria from obese mice to be similar to that of lean mice,» Noratto said.

A common antioxidant found in human breast milk and foods like kiwi fruit can protect against nonalcoholic fatty liver disease (NAFLD) in the offspring of obese mice, according to researchers at the University of Colorado Anschutz Medical Campus.

«When given to obese mouse mothers during pregnancy and lactation, we found it protected their offspring from developing symptoms of liver fat and damage that leads to NAFLD in early adulthood.»

«Importantly, we found that blocking the actions of the endocannabinoids with pharmacological inhibitors of cannabinoid receptors in the periphery completely normalized food intake and meal patterns in western diet - induced obese mice to levels found in control lean mice fed standard chow.»

«We did not do it using a genetic strain of obese mice, but mice that became obese the way that people do, by eating a high - fat, high - sugar diet.»

Protective antibodies from lean mice also failed to protect obese mice from flu infections.

Obese mice were not.

The investigators also discovered that a potent suppressor of autophagy (called mTOR) was hyperactivated in the kidneys of obese mice, and treatment with an mTOR inhibitor ameliorated autophagy insufficiency.

«Vaccines fail to protect obese mice from severe influenza infections: Fu vaccines with adjuvants don't work as well in obese mice.»

«The virus penetrates more deeply into the lungs of obese mice, and the animals seem to have a more difficult time repairing the damage,» Schultz - Cherry said.

Maratos - Flier's lab hopes to explore whether obese mice given the hormone will get lean again.

«This is the first study to show that current strategies to bolster the effectiveness of flu vaccines protected lean mice from serious illness but fell short of protecting obese mice from infections,» said corresponding author Stacey Schultz - Cherry, Ph.D., a member of the St. Jude Department of Infectious Diseases.

The obese mice seemed more susceptible to the virus, which remained elevated following vaccination compared to blood levels in lean animals.

Researchers looked at the immune response to vaccination in lean and obese mice, including how vaccine dose and different adjuvants impacted that response.

While adjuvants improved the immune response to vaccinations in both lean and obese mice, the overall immune response was reduced in the obese animals compared to their lean counterparts.

Whole - body vibration, the activity this gym - goer is performing, provided a metabolic tune - up for obese mice.

In research published in December 2013, the investigators found that high levels of IKK - ε and TBK1 meant that certain receptors in the fat cells of obese mice were unable to respond to neurotransmitters called catecholamines, which are generated by the sympathetic nervous system and promote «fat - burning.»

By comparing the behavior of XBP - 1s in the obese mice with that in lean, healthy ones, he discovered an inflammatory protein that modifies XBP - 1s in healthy animals so it can be shuttled into the nucleus.

«Understanding how the drug also enables crosstalk between fat cells and the liver in obese mice allows us to see more of the amlexanox picture — and also sheds light on communication between different tissues in the body.»

Obese mice gained less weight after exercise or WBV than obese mice in the sedentary group, although they remained heavier than normal mice.

The inhibitor we discovered successfully relieved the symptoms of type II diabetes in obese mice and not only elevated their insulin levels but promoted healthy insulin signaling within the blood.»

The obese mice had a leptin deficiency — and an insatiable appetite.

Research conducted at the University of Barcelona showed that obese mice living on a diet enriched with omega - 3s displayed improved sensitivity to insulin.

In obese mice, activation of this receptor stimulates orexin A release.

The study shows that a hormone acting on the placenta can protect the offspring of obese mice from being born overweight.

The researchers also studied the effect of switching off hunger neurons in obese mice.

They found that the obese mice showed structural changes in their testes and changes in sex hormone expression.

New study shows that in obese mice a hormone secreted by fat cells goes undetected and the regulation of appetite is thrown off; findings could trigger treatment

In their research the team blocked a particular inflammatory signalling pathway (IKKβ / NF - κB) in the brains of obese mice.

The researchers gave adiponectin intravenously to obese mice during the last 4 days of their roughly 3 - week - long pregnancies — when the majority of fetal growth occurs.

But Kahn's team at Beth Israel Medical Deaconess Center found that they could create obese mice that were unusually sensitive to insulin.

When the Cornell team cultured human breast cancer cells on matrix deposited by fat - derived cells from obese mice, the cancer cells grew faster than they did on the matrix of cells from slimmer mice.

While hardly any inflammation occurred in the subcutaneous fat of obese mice and cGMP signaling was largely intact, things were very different for the deeper - lying abdominal fat: through the significant weight increase, inflammation had spread and the fat - burning turbocharger cGMP largely came to a standstill.

The news wasn't all bad: When Fischbach's team put obese mice on a diet, their mammary fat tissue had fewer myofibroblasts, suggesting losing weight could make a woman's fat tissue structure more normal and lower her breast cancer risk.

Kravitz has a background in studying Parkinson's disease, and when he began conducting obesity research a few years ago, he was struck by similarities in behavior between obese mice and Parkinsonian mice.