My Functional Medicine GP who specialises in Chronic Diseases suggested
Ketogenesis as a way to help me reach my health goals.
Not exact matches
Therefore, when insulin levels are high, fatty acids are not well used
as fuel and no significant
ketogenesis occurs.
Research also suggests that coconut oil may directly stimulate
ketogenesis in astrocytes and provide fuel to neighboring neurons
as a consequence, thus improving brain health (Nonaka et al., 2016).
As shown previously [Rabinowitch & Smith, 1936], though the small amount of carbohydrates in the diets may be more than balanced by the potential sugar production from the large amount of protein to keep the ratio of fatty acid to glucose below the generally accepted level of
ketogenesis, the respiratory quotient data suggest another mechanism also.
When mice are genetically modified to lose Nrf2 function, they also lose many of the anti-inflammatory and antioxidant benefits of isocyothianate exposure, further linking cruciferous vegetables and Nrf2.41 Studies even suggest that Nrf2 is required to gain the beneficial effects of isocyothianates, connecting the benefits of exercise, fasting, periodic
ketogenesis, and healthy cellular stresses with vegetable and spice consumption,
as they all can stress our cells and engage Nrf2.42
Dr. Bredesen described a 36 point intervention that included such things
as optimizing sleep, aerobic exercise, keeping homocysteine below 7, reducing simple carbohydrates, increasing
ketogenesis, keeping A1c below 5.5, optimizing vitamin D levels, reducing grain consumption, and adding sources of good fat for the brain like coconut oil.
The process of creating KBs is known
as ketogenesis.
Lactate, which increases during starvation, can induce hepatic
ketogenesis.2 Low - carbohydrate, fat - rich meals can enhance alpha - cell secretion of glucagon and lower insulin concentrations.3, 4 Plasma fatty acid concentrations can be twice
as high during low - carbohydrate diets
as compared with the usual carbohydrate intake in the postabsorptive period.5 Increased concentrations of free fatty acids in the absence of carbohydrate - induced inhibition of beta - oxidation of fatty acids and in the presence of an abnormally high ratio of glucagon to insulin and elevated concentrations of lactate may have caused ketoacidosis in our patient, who was trying to avoid all dietary carbohydrates.