Here we show that the frequency of CD8 + T cells expressing the inhibitory
killer cell lectin - like receptor G1 (KLRG1), a marker of cells unable to undergo further clonal expansion, was markedly elevated in CD8 + T cells from old donors.
Here we consider two surface markers thought to define these cells in mice, CD8 and
Killer cell lectin - like receptor G1 (KLRG1), and a means we developed to remove these cells from the blood of aged C57BL / 6 mice.