Western Diet — Induced Dysbiosis in Farnesoid X Receptor
Knockout Mice Causes Persistent Hepatic Inflammation after Antibiotic Treatment — Prasant K — The American Journal of Pathology
Not exact matches
In this study, by using a systemic mtEF4 gene
knockout mouse model, researchers found that mtEF4
knockout damages the oxidative phosphorylation function in germ cells of male
mice, thus
causing male sterility.
An international team of researchers has identified a
cause for chronic bad breath (halitosis), with the help of gene
knockout mice from the UC Davis
Mouse Biology Program.
Now that they have a FAN1
knockout mouse in hand, and they have confirmed that it mimics many aspects of karyomegalic interstitial nephritis in humans, Smogorzewska's lab can start to delve into how the loss of the gene
causes kidney degeneration.
The fact that Connexin 30
knockout mice had a higher number of grafted cells than normal
mice, and that some of the grafted cells expressed CONNEXIN 30 is a very important finding when considering cell transplantation as a treatment for hereditary hearing loss
caused by CONNEXIN deficiency.
In other research, a
knockout of the gene that encodes one type of lncRNA in
mice conferred some resistance to obesity
caused by a high - fat diet.
Here, we demonstrate that astrocytes are a direct insulin target in the brain and that
knockout of IR on astrocytes
causes increased anxiety and depressive - like behaviors in
mice.
However, this significant reduction in adipose mass does not
cause the overt metabolic dysfunction seen in Bscl2
knockout mice, even following a high - fat diet challenge.
P. Gupta, et al., Disruption of PPT1 or PPT2
causes neuronal ceroid lipofuscinosis in
knockout mice, Proc.