Sentences with phrase «laboratory mice live»

Not exact matches

However, in some studies with laboratory mice, Feinberg had observed that these epigenetic tags varied considerably among the mice even when comparing the same type of tissue in animals that have been living in the exact same conditions.

In laboratory tests on embryonic mice engineered to not express myomerger in skeletal muscle, the animals did not develop enough muscle fiber to live.

Laboratory mice that have received rapamycin have reduced the age - dependent decline in spontaneous activity, demonstrated more fitness, improved cognition and cardiovascular health, had less cancer and lived substantially longer than mice fed a normal diet.

Aside from a food intake in laboratory mice that's about 40 percent fewer calories than normal, however, it's been found that another way to activate this pathway is with rapamycin, which appears to have a significant impact even when used late in life.

For example, it could be used to image neurons in living mice by combining the Raman scattering technique with existing methods in which tiny windows are implanted in the brains and spinal cords of laboratory animals.

The findings have implications for all aspects of medical and scientific research because laboratory mice underpin studies whose results have a transformative effect on human and animal lives through vaccination and other immune - based therapies.

In a seminal series of experiments beginning in the 1960s, Walford studied the effect of depriving laboratory mice of calories and discovered that the less they ate — within reason — the longer they lived.

In addition, the mutant mice responded better to treatment with chemotherapy», says Lena Claesson - Welsh, professor at the Department of Immunology, Genetics and Pathology, at Uppsala University and Science for Life Laboratory, who led the study.

«We think that by restoring the natural «microbial identity» of laboratory mice, we will improve the modeling of complex diseases of free - living mammals, which includes humans and their diseases,» said Barbara Rehermann, M.D., senior author of the paper.

That's because most studies on single human brain cells use dead rather than living tissue, and many others rely on cells from common laboratory animals, especially mice.

«We hypothesized that this might explain why laboratory mice, while paramount for understanding basic biological phenomena, are limited in their predictive utility for modeling complex diseases of humans and other free - living mammals,» said Rosshart.

About 25 million mice are used in laboratories around the world to test new drugs and new notions about the biochemical machinery of living organisms.

Gold nanotubes engineered to a specified length, modified surfaces, and to have other desirable characteristics showed expected abilities to enter tumor cells in laboratory studies, and to distribute to tissues within live mice as intended.

In the Finkbeiner laboratory, Linsley uses time - lapse imaging of neurons in culture, within organotypic mouse brain slices, and within live zebrafish to uncover the mechanisms in neurodegeneration that lead to neuronal death.

He was the first to engineer mice that develop the cerebral plaques and tangles that characterize Alzheimer's, providing researchers with a crucial «living laboratory» of the disease.

When maintaining a live colony at The Jackson Laboratory Repository, homozygous mice may be bred together.

A breed of dwarf mouse that entirely lacks growth hormone is the present winner of the Mprize for longevity, living 60 - 70 % longer than the compeition's standard laboratory mouse species.

All mice were bred and housed in specific pathogen - free conditions at the Association of Laboratory Care - approved animal facility at the Life Science Addition, University of California, Berkeley, CA.

However, if live mice are sent to EMMA or if live mice are requested from the archive, EMMA ensures that mice are shipped according to conditions that comply with LASA (Laboratory Animals Science Association) guidelines.

Every living thing on the planet will naturally work to attain greater resources / mating opportunities, etc... In countless laboratory experiments, using a variety of species, from mice to primates, animals who were trained to work for rewards, continued to do so, even when given free access to another food supply.

Intensive work with live laboratory animals including mice, rats, hamsters, guinea pigs, and rabbits