In 2016, an examination of the peer - reviewed scientific literature has uncovered dozens of paleoclimate reconstructions that reveal modern «global» warming has not actually been global in scale after all, as there are
a large number of regions on the globe where it has been cooling for decades.
Not exact matches
There are also few fitness facilities, a
large number of fast - food chains, and housing is pricey for the
region.
One
large franchise owner would have the role
of developing a certain
number of restaurants in a particular
region over a period
of time, putting up their own capital to do so and perhaps subfranchising to individual owners.
More favourable growing conditions this season should lead to a sharp increase in the
number of red and white grapes crushed, while
regions such as Swan and Manjimup should continue to see increasingly
larger yields over the next five years.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount
of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a
larger than anticipated shift in payer mix to more highly discounted payer segments and geographic
regions and decreases in treatment duration; availability
of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction
of generic versions
of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect
of lowering prices or reducing the
number of insured patients; the possibility
of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels
of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits
of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages
of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development
of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate
of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
As shown in the graph below, the
number of immigrants from the Asia Pacific
region is fairly
large compared to other
regions.
With a fixed
number of 600 components, the STOXX Europe 600 Index represents
large, mid and small capitalization companies across 18 countries
of the European
region.
Today, Powerline Plus boasts the
largest number of employees
of any company
of its kind in the
region offering full turnkey solutions to the market.
«It's not a nurturing space — the
region, in general, is not an interesting space for tech, the
larger numbers are in gaming or tourism,» Lang,
of UNLV, said.
But as a
number of large global banks have recently exited the
region, Duraiswamy says this has accelerated the growth in market share
of local banks and
large regional banks in trade and cash management.
In addition, the ongoing war with Yemen, the abrupt resignation
of Lebanon's Prime Minister Saad Hariri from Saudi soil, and the internal power struggle within the Saudi monarchy leading to the detention
of a
large number of powerful members from the royal family sum up the major ongoing conflicts in the
region.
But famine, like a plague, spreads, and, «In reality it's a very
large food security crisis involving a
number of countries and millions at risk,» said Golden, referring to the crisis situation in vast
regions of east Africa.
Now RAAW ™ Juices are available in Von's Pavilions, Raleys, Marsh, Giant Eagle, Tops, The Fresh Market, SuperValu, Safeway, a
number of Whole Foods
regions and
larger supermarket chains, as well as the smaller independents in which RAAW ™ Juices were first introduced.
It's official: Asia Pacific's ever - growing network
of economies has topped North America and Europe as the
region with the
largest number of wealthy citizens in the world.
According to data from the Ministry
of Agriculture, in November 2015 were recorded 11.478 organic producers units, being the South
region the
largest number of production units representing around 36 %
of the total, followed by the Northeast (32 %) and South (21 %).
For the past three years Paul has headed the
largest division
of Accolade Wines, the UK and Ireland
region, where the business is the
number one wine company by value and volume, more than double the size
of its nearest competitor.
If an all - inclusive resort is not your thing, there are a
number of self - catering options throughout the
region, and Playa Del Carmen is home to a couple
of large supermarkets — a Sam's Club and the Mexican chain Mega are located on the main highway that runs between Cancun and Tulum.
The
number of Long Islanders served by one
of the
region's
largest food banks increased by 19 percent last year despite the improving economy, according to the Hauppauge - based nonprofit.
During his remarks at the University at Albany, Cuomo — who delivered six addresses across New York between Monday and Wednesday, rather than deliver one address in the state's capital — touched on a
number of topics relevant to both the Capital
Region and the state at
large, ranging from water infrastructure improvement to revitalization
of upstate business.
Amedore has sure done a lot for that
region since being seated... no wonder he is contemplating not running this November when
large numbers of Dems will be engaged!.
For a
region this
large, the woeful
number of such assets is embarrassing.
Since then, lawmakers who represent areas with
large numbers of state workers in their districts — the Capital
Region and Long Island — have written to the Cuomo administration urging them to take action on the issue.
A
large number of angry NPP Youth groups from Amenfi Central, Amenfi East, Prestea and some places in the Western
Region who met with the flagbearer
of the New Patriotic Party Nana Akufo - Addo yesterday, questioned him about the whereabouts
of the party's National Chairman Paul Afoko, General Secretary Kwabena Agyepong and the Vice Chairman Sammy Crabbe as they didn't see any
of them on the campaign tour.
It has been tested by a
large number of local authorities in the United Kingdom for their elections, and in 2004 it was used for elections to the European Parliament and local authorities in four
of the English
regions (see below for more details).
But given the
large number of colleges and universities in the
region, Mager said, it's likely Sanders will make a stop at a Central New York school in early April to rally his base
of young supporters.
He said in - spite
of the challenges the
region recorded the
largest number of trainees from all the districts in the
region.
Long Island and the lower Hudson Valley currently have the
largest numbers of mute swans, but a rapidly increasing population has taken hold in the Lake Ontario
region, the DEC stated.
Cuomo ended up winning handily, though Teachout won majorities in a
large number of upstate counties, including in the Capital
Region.
Rural
regions lost
large numbers of residents (Allegany County, 2.47 percent; Cattaraugus County, 2.14 percent; and Chautauqua County, 2.11 percent) while suburban towns had mixed results (Amherst's population grew by 2.12 percent, while Cheektowaga's dropped by 0.44 percent and Tonawanda's declined by 0.17 percent).
«Wontumi has misled the media and police in a wild goose chase
of large cache
of ammunition and thumb printed ballot papers across the
region, from an initial false claim
of an impounded ammunition by the military in Kumasi, to the search
of house
numbered AS2015S at Asouyeboa for weapons and ended with another in Tanoso yesterday.»
A
large number of Labour - held metropolitan boroughs are up for election in this
region, which is likely to bring out the party's vote in greater
numbers than if the European elections were held alone.
That represents the
largest number of projects in any
region of the state and the
largest dollar investment
of any Upstate
region.
With a
large number of electrode channels distributed across the scalp, this method also detects which brain
regions show more slow - wave activity than others.
Dr. Julie Wolf, U.S. Department
of Agriculture (USDA), Agricultural Research Service (ARS), senior author
of the study said: «In many
regions of the world, livestock
numbers are changing, and breeding has resulted in
larger animals with higher intakes
of food.
Additionally, researchers found that the Rocky Mountain
region, with its
large number of wells with a high frequency
of unloadings that vent to the atmosphere, accounts for about half
of overall emissions from liquid unloadings.
The much
larger variations
of up to 10oC occuring as the Sun and Earth travel through the Galaxy visiting
regions with varying
numbers of exploding stars.
Last spring a research team led by Michael Tippett, associate professor
of applied physics and applied mathematics at Columbia Engineering, published a study showing that the average
number of tornadoes during outbreaks —
large - scale weather events that can last one to three days and span huge
regions — has risen since 1954.
Running produced a
large increase in the
number of new neurons in the hippocampus — a brain
region shown to regulate anxiety —
of a mouse that ran for six weeks (above).
In the crowded central
regions of the galaxy, home to
large numbers of massive stars, supernovas are so common that the evolution
of complex life - forms might be difficult if not impossible.
They identified three genes (FANCL, VRK2 and BCL11A) associated with
large numbers of accelerated
regions of evolution.
The authors systematically analyzed a
large number of flies in which different patches
of neurons lacked dati, and were able to map the rejection behavior to three distinct
regions in the brain, two
of which had never been previously associated with mating behavior.
[2] This quantity is in fact much
larger than the
numbers quoted by previous studies which surveyed smaller
regions, leaving out many
of the cluster's stars that lie further from its core.
We see great cultural diversity and
large numbers of cultures per unit area in
regions of the world in which the environment is really rich.
Tilted pillars, cracked steps, and sliding stone canopies in a
number of 7th - century A.D. temples in northwest India are among the telltale signs that seismologists are using to reconstruct the extent
of some
of the
region's
larger historic earthquakes.
They chose this
region because it has a
large number of cells and because the bird's feet hadn't been treated with arsenic, leaving the DNA there in better shape than on the rest
of the preserved carcass.
Now new research shows that these eruptions on the sun's surface not only send bursts
of energetic particles into Earth's atmosphere causing disturbances in the magnetic field, but they may also significantly decrease the
number of free electrons over
large areas in the polar
region of the ionosphere — the ionized part
of the upper atmosphere.
Exhaustive contact tracing requires
large numbers of staff, and is challenging both in dense urban areas and in remote
regions that are difficult to reach.
In this case, a hypothetical particle called a graviton — which mediates gravity — appears in
large numbers out
of the vacuum
of space in
regions crowded with massive objects such as stars.
The Himalayan range encompasses a very
large number of glaciers, notable among which is the Siachen Glacier, the
largest in the world outside the polar
region.
More than 600
large dams have been built or are in some stage
of construction or planning in the geologically active Himalayan Mountains, but many are probably not designed to withstand the worst earthquakes that could hit the
region, according to a
number of seismologists and civil engineers.