Sentences with phrase «large trials showed»

Large trials showed exercise's association with reduced all - cause mortality and that self - reported moderately vigorous physical activity led to lower risk of all - cause and cancer - specific mortality.

A large trial showing that men with newly diagnosed, advanced prostate cancer lived ten months longer, on average, when they received docetaxel chemotherapy along with standard hormone therapy

If this and other large trials show that NSAIDs are truly effective, then doctors may start to recommend them to women for breast cancer risk reduction.

Not exact matches

While the new mid-stage study results from DNDi were impressive (they showed cure rates of 96 % to 97 % even for the sickest patients and those with liver scarring), more late - stage trials will be necessary before the drug is available on a large scale in the developing world.

Although some of the enthusiasm for home visiting has waned in the past decades as reports of some large randomized trials have failed to demonstrate program effects, evidence from other programs targeted for families at risk (eg, low - income families) has shown enough promise to build on program development momentum.

«Protein in breast milk reduces infection risk in premature infants: Study shows need for large - scale trial of lactoferrin's role in immune system development.»

The protective effects of breast feeding have been shown to be dose responsive16 17 18 and minimal breast feeding may not be protective.17 Researchers in lactation have advocated that research on promotion of breast feeding must target exclusive breast feeding, 19 and ours is one of the larger randomised controlled trials with this primary outcome.

«This is the largest randomized trial of any behavioral intervention in children with autism spectrum disorder, and it shows that parent training works,» notes Lawrence Scahill, MSN, PhD, professor of pediatrics at Marcus and Emory School of Medicine, who directed the study.

Another method, if one goal was to smooth out sudden generational shifts, would be to appoint some larger pool of full Justices, not acting as subs, but as a full rotating roster, [something like one of those watches or clocks that shows phases of the moon], advancing by one justice per trial.)

Large donors included public employee and trade unions, the Empire State Pride Agenda (gay rights) and Lawpac of NY (trial lawyers), records show.

But this study showed that acupuncture added nothing beyond medication,» said Legro, who noted that this large trial is one of the highest quality acupuncture trials to address fertility outcomes.

He points out that the largest trials of antihypertensive therapy and statins for people in this age group have shown only a marginal reduction in stroke and very modest reductions in other cardiovascular events.

A large Australian trial showing that daily use of nicotinamide, a form of vitamin B3, for 12 months reduced the incidence of new non-melanoma skin cancers by 23 % in patients at high risk for skin cancer

A clinical trial has shown that patients with a specific molecular subtype of diffuse large B - cell lymphoma (DLBCL) are more likely to respond to the drug ibrutinib (Imbruvica) than patients with another molecular subtype of the disease.

Most clinical trials show that cutting out 1,000 milligrams of sodium from a diet, a relatively large amount, results in only a small drop in blood pressure on average, Cohen says.

«We have shown that a large number of study participants are routinely exposed to the risks of trial participation without the benefits that sharing and publishing results would have for patients in the future.

This finding helps explain why two large clinical trials testing HIV pre-exposure prophylaxis, or PrEP, in women failed to show efficacy.

The team's next step will be to complete studies showing safety of SW033291 - related compounds in larger animals, a required part of the pathway to secure approval from the U.S. Food and Drug Administration for trials in humans.

Despite lowering low - density lipoprotein (LDL), known as «bad» cholesterol, while markedly increasing levels of high - density lipoprotein (HDL), or «good» cholesterol, a large clinical trial to investigate the cholesterol drug evacetrapib was discontinued early after a preliminary analysis showed it did not reduce rates of major adverse cardiovascular events, according to research presented at the American College of Cardiology's 65th Annual Scientific Session.

A large randomized controlled trial of ischemic postconditioning in patients who had experienced the deadliest form of heart attack — ST - segment elevation myocardial infarction (STEMI)-- failed to show that this procedure significantly reduces death from any cause or hospitalization for heart failure, according to research presented at the American College of Cardiology's 65th Annual Scientific Session.

The disturbing first results of a long, large - scale trial of the AIDS drug AZT show that patients who start treatment early in the course of HIV infection fare no better than those who wait until they begin to suffer symptoms.

Previous studies, including large - scale trials in China, have shown that cruciferous vegetables that have a high concentration of sulforaphane — such as broccoli, cabbage and garden cress — help mitigate the effects of environmental carcinogens.

And it remains true that no homeopathic remedy has ever been shown to work in a large randomised placebo - controlled clinical trial.

The study is the first large trial to show radial access improves patient outcomes and that it reduces dangerous bleeding beyond the bleeding that can occur near where the catheter is inserted.

The eagerly awaited results from the world's first large - scale trial of a malaria vaccine are in, and they confirm what other, smaller studies had shown: The vaccine, called RTS, S, offers partial protection, cutting episodes of malaria in babies and toddlers in half.

The current study combines data from five clinical trials involving a total of 1,287 people, including the SWIFT PRIME trial led by Saver, that show these devices improved outcomes for people with acute ischemic strokes due to large vessel blockage.

Yet large - scale clinical trials supplementing participantsâ $ ™ diets with antioxidants have showed little benefit.

4/14/2008 Statins Shown to Lower Blood Pressure A large, randomized drug trial has shown for the first time that statin drugs result in a modest, but significant, reduction in blood presShown to Lower Blood Pressure A large, randomized drug trial has shown for the first time that statin drugs result in a modest, but significant, reduction in blood presshown for the first time that statin drugs result in a modest, but significant, reduction in blood pressure.

CREST - E, the largest clinical trial of the dietary supplement creatine, has been terminated early because an early analysis of the results to date showed there was no realistic chance it could show positive results.

Now, on Nov. 5, a news story likened those findings to the results of a large trial by the National Cancer Institute, which showed that CT scans reduced mortality rates among the highest - risk lung cancer patients by 20 percent.

Potential cardioprotection was based on generally supportive data on lipid levels in intermediate outcome clinical trials, trials in nonhuman primates, and a large body of observational studies suggesting a 40 % to 50 % reduction in risk among users of either estrogen alone or, less frequently, combined estrogen and progestin.2 - 5 Hip fracture was designated as a secondary outcome, supported by observational data as well as clinical trials showing benefit for bone mineral density.6, 7 Invasive breast cancer was designated as a primary adverse outcome based on observational data.3, 8 Additional clinical outcomes chosen as secondary outcomes that may plausibly be affected by hormone therapy include other cardiovascular diseases; endometrial, colorectal, and other cancers; and other fractures.3, 6,9

However, with few exceptions, the stem cell and regenerative medicine industry has remained inadequately capitalized to carry out large - scale clinical trials independently, and major pharmaceutical firms have tended to show more interest in the use of hiPSCs as a source of large, pure populations of specific somatic cells for use in drug compound screening and toxicology tests, than they have in therapeutic uses of stem cells and their derivatives.

However, another large randomized sham - controlled trial of TMS added to antidepressant pharmacotherapy showed no significant benefit of left dorsolateral prefrontal cortex TMS.

Study in partnership with the Alliance for Clinical Trials in Oncology is the first large controlled trial to show overall survival benefit in FLT3 - mutated AMLAML is the most common acute leukemia in...

MHRP is proud to have led a large group that executed the landmark RV144 vaccine trial, the first study to show efficacy in preventing HIV infection.

For the first time, a large clinical trial showed across - the - board cardiovascular benefit of a diabetes drug — liraglutide — a much - needed outcome for people with type 2 diabetes.

Because not only is γ - tocopherol responsible for scavenging RNS, but large doses of α - tocopherol displace γ - tocopherol in plasma and other tissues, the current wisdom of vitamin E supplementation with α - tocopherol alone may produce an imbalance that contributes to cancer and heart disease.13 Adding support to this hypothesis, a recent clinical trial of individuals suffering from coronary heart disease showed decreased serum levels of γ - tocopherol, but not α - tocopherol.14

One large randomized, double - blind, placebo - controlled trial showed that MYO (4 g / day) for 14 weeks, increased HDL («good» cholesterol) levels and resulted in significant weight loss (and decreased leptin levels) in women with PCOS, although no change in insulin was detected.

While further large - scale trials are needed, Vitamin K2 has been shown to increase bone density.

Whereas diets high in fat have been shown, again and again, in a large body of clinical trials, to lead to improved measures for heart disease, blood pressure, and diabetes, and are better for weight loss.

Similarly, randomized controlled trials in which yoga was used to alleviate the pain of osteoarthritis in the knee have shown larger improvements in walking pain, knee disability, joint tenderness, swelling and crepitus, as well as greater range of motion when compared to therapeutic exercises or a combination of transcutaneous stimulation and ultrasound treatment.

The largest intervention study on a vegan diet that I know of showed better overall nutrient intake, but calcium was one nutrient that was very low Nutrient intake in the GEICO multicenter trial: the effects of a multicomponent worksite intervention.

Specifically, from 2003 — 2005 Boston's fourth - and eighth - grade students have shown the largest improvement in math scores of the 11 major cities participating in the National Assessment of Educational Progress Trial Urban District Assessment.

(Long - 26 minutes) Presentation on spreadsheet to show that the normal distribution approximates the binomial distribution for a large number of trials.

The therapeutic dotential of dietary precursor modulation by a fish - oil - supplemented diet (n - 3 fatty acids), such as eicosapentaenoic acid (C20: 5,n - 3) and docosahexaenoic acid (C22: 6,n - 3) in the therapy of ulcerative colitis has been shown to result in a 35 % to 50 % decrease in neutrophil production of LTB4.28 Significant improvement in symptoms and histologic appearance of the rectal mucosa has been observed in several small series of patients with Crohn's disease and ulcerative colitis given fish oil at 3 to 4 g daily for 2 to 6 months in uncontrolled studies.29 However, a larger, randomized, double - blind trial comprising 96 patients with ulcerative colitis failed to reveal any benefit in remission maintenance or treatment of relapse on 4.5 g of eicosapentaenoic acid daily, despite a significant reduction in LTB4 synthesis by blood peripheral polymorphonuclear cells.30 It should be emphasized, however, that the anti-inflammatory actions of the fish oils, in addition to inhibition of LTB4, include suppression of IL - 1 and platelet activating factor synthesis and scavenging of free oxygen radicals.30 The impact of increased lipid peroxidation after fish oil supplementation should be considered when altering the n - 6: n - 3 fatty acid ratio.31 Antioxidant supplementation may be able to counteract the potentially adverse effects of n - 3 fatty acids.

Although UKC registers more breeds, AKC is larger and has broader impact on the world of purebred dogs through its extensive network of education and legislative coordinators, free education program for students, contributions to canine health, administration of a microchip identification registry, and involvement in more than 15,000 dog shows, tests, and trials each year.

Unfortunately, many scientific trials have shown that whereas plants do grow faster and often larger under high CO2, they often have lower protein levels so are less useful as food.

Via:: Green Car Congress: Large Field Trial Shows Miscanthus Could Meet US Biofuels Goals With Less Land (news website)

Saturday marks the start of the annual meeting of the American Association for Justice (f / k / a Association of Trial Lawyers of America), and the AAJ is setting the stage with today's release of a survey showing that voters distrust large corporations far more than they do trial lawTrial Lawyers of America), and the AAJ is setting the stage with today's release of a survey showing that voters distrust large corporations far more than they do trial lawtrial lawyers.

Several times a year, not enough people show up at the municipal court in response to jury summonses to provide a jury pool large enough to conduct a trial on a day where someone facing criminal charges must be tried or have their charges dismissed on speedy trial grounds.