Sentences with phrase «leukocyte antigen»

Testing for the human leukocyte antigen HLA - B * 5801 allele before initiating allopurinol was found to be cost effective for black and Asian patients but not for white or Hispanic patients, according to results of a cost - effectiveness analysis published in Seminars in Arthritis and Rheumatism.

Evidence is mounting for a genetic basis for canine diabetes, and the association with the major histocompatibility complex alleles on the dog leukocyte antigen gene strongly suggests that the immune response has a role in pathogenesis.

Testing for the human leukocyte antigen HLA - B * 5801 allele before initiating allopurinol was found to be cost effective for black and Asian patients but not for white or Hispanic patients...

Chronic pancreatitis is recognized as a distinct cause of diabetes in people, because affected insulin - dependent individuals do not have the immunological phenomena or the association with leukocyte antigen alleles that characterize type 1 diabetes (96).

Organ transplantation is a challenge, requiring immunosuppressive drugs and careful matching of donor and recipient for human leukocyte antigen markers, receptors on immune cells that recognize foreign proteins.

Using FACS we also found that all of the F4 / 80 + cells coexpressed the common leukocyte antigen CD45 and the monocyte lineage marker CD11b (data not shown).

Dr. Tsai is currently sequencing dog leukocyte antigen class I and II loci and assigning alleles for a funded study to evaluate if certain alleles are associated with pancreatic acinar atrophy (EPI)

The Major Histocompatibility Complex (MHC) is a region of the genome that contains genes that code for a group of cell surface proteins known as Dog leukocyte antigens (DLA).

A team at Stanford University focused on human leukocyte antigen (HLA) class 1 genes, which play a vital role in rallying the immune system to fight off bacteria and viruses.

The human leukocyte antigen (HLA) region, which is specific to peanut allergy cases, appears to be the only exception.

His research at Roche Molecular Systems involves analysis of human genetic variation and genetic predisposition to a variety of diseases, with a focus on autoimmune diseases (in particular type 1 diabetes), and the development of HLA (human leukocyte antigen) typing tests.

The second cohort of 140 patients with human leukocyte antigen - matched unrelated donor transplants completed enrollment in November 2017, with data expected from this randomized double - blind arm of the study in the next six months.

On the other hand patients with DRB1 * 04:01 have a better clinical outcome in the short - and long - term suggesting that human leukocyte antigen (HLA) analysis and screening for SLA / LP antibodies should be integrated in the clinical routine for AIH diagnosis.

The HLA (human leukocyte antigen) is a system of genes responsible for regulating immune responses, and peptides are short chains of amino acids that play key roles in regulating the activities of other molecules.

He focused on human leukocyte antigens (HLAs), a family of about 200 genes that is essential to our immune system.

All people have human leukocyte antigens (HLA), proteins that are key to the immune system's defense against bacteria, viruses and other potentially harmful invaders.

They instead implicate immune genes called human leukocyte antigens (HLAs), which are central to our body's ability to detect invading pathogens.

But human leukocyte antigens — a group of genes that encode proteins essential to the human immune system — in the samples showed that a few individuals had a type, or allele, found among only Native Americans.

Narcoleptics are also likely to have a specific variant of the human leukocyte antigen.

The mice they studied are engineered to express human leukocyte antigen, which helps regulate the human immune system, and, in this case, helped the mice produce the powerful T cells again human cancer.

HLA (human leukocyte antigen)- markers on the surface of a body's cell that identify the cell as one's own (as opposed to a foreign cell) and prevent the immune system from attacking itself.

The cells or blood is then tested for special proteins, called human leukocytes antigens (HLA).

Most genes known to be associated with type 1 diabetes — including those currently considered the top two high - risk genes, which are the ones TEDDY screens for — are classified as human leukocyte antigen, or HLA genes.

An off - the - shelf, universal product doesn't require human leukocyte antigen (HLA) matching of the donor and recipient.

In the early 1980s, scientists at the University of Tokyo found that all of their narcolepsy patients had the same form of the human leukocyte antigen, or HLA.

The most potent of these, known as effector memory T cells, are activated by a group of proteins known as human leukocyte antigens (HLAs) on the surface of endothelial cells lining the donated organ's blood vessels.

HLA stands for human leukocyte antigen.

Patients receive one of two types of stem cell - based transplants: autologous, in which a patient donates and receives back his / her own stem cells; or allogeneic, in which bone marrow - derived stem cells come from a related or unrelated donor whose human leukocyte antigens (HLA) are genetically matched with those of a patient.

The human leukocyte antigen (HLA) system is a gene family that encodes the human major histocompatibility complex (MHC).

Velimogene aliplasmid (Allovectin - 7), a plasmid / lipid complex with human leukocyte antigen (HLA)- B7 and β2 microglobulin DNA encoding sequences, was granted orphan drug designation by the FDA back in 1999.

Revealed that the loss of the human leukocyte antigen (HLA) locus in lung cancers is a way these tumors evade the immune system and allow mutation expansion and branched evolution within tumor cells

Forty percent of patient - derived tumors his team examined had tumor cells that stopped producing human leukocyte antigen (HLA)-- a molecule necessary for the presentation of antigens on a cell's surface, to be recognized by immune cells.

Currently there are several known genes associated with Hashimoto's thyroiditis: cytotoxic T - lymphocyte associated antigen 4 (CTLA - 4), human leukocyte antigens (HLA), protein tyrosine phosphatase 22 (PTPN22) and thyroglobulin receptor gene.

We don't limit ourselves just to the HLA test (human leukocyte antigen) which are the genes in the immune system that are related to attraction.

HUFFINGTON POST - Nov 8 - A Swiss company called GenePartner has developed a biological matching system using your human leukocyte antigen, or HLA, genes to find your perfect match.

Human type 1 diabetes is principally a disease of Caucasians, and the major genetic susceptibility is linked to the major histocompatibility complex alleles on the leukocyte antigen gene on chromosome 6p, although many other genes contribute (74).

We demonstrated significant differences in dog leukocyte antigen (DLA) haplotype frequencies in six of these breeds: Cocker spaniel, Springer spaniel, Labrador, West Highland white terrier (WHWT), Bearded collie, and Standard poodle.

Preliminary sequence analysis of the dog leukocyte antigen (DLA) gene in a heterogeneous population of canine diabetics revealed that one haplotype is overrepresented (84,89).

The Major Histocompatibility Complex (MHC) is a region of the genome in dogs that contains genes that encode a group of cell surface proteins known as Dog leukocyte antigens (DLA).

This study examines genetic diversity among 102 registered English Bulldogs used for breeding based on maternal and paternal haplotypes, allele frequencies in 33 highly polymorphic short tandem repeat (STR) loci on 25 chromosomes, STR - linked dog leukocyte antigen (DLA) class I and II haplotypes, and the number and size of genome - wide runs of homozygosity (ROH) determined from high density SNP arrays.

Our natural smell, is produced, in part, by genes called human leukocyte antigens (HLA).