Sentences with phrase «lifecourse epidemiology»

Paediatric and Lifecourse Epidemiology Research Group, Child Health, School of Clinical Medical Sciences

New research from the MRC Lifecourse Epidemiology Unit at the University of Southampton in the UK indicates that neighbourhood exposure to fast food outlets is potentially linked to poorer bone development in early childhood.

Researchers from the Medical Research Council Lifecourse Epidemiology Unit, University of Southampton, used high resolution peripheral quantitative computed tomography (HRpQCT) to assess bone structure and strength at a microstructural level in living patients.

Professor Cyrus Cooper, Director of the MRC Lifecourse Epidemiology Unit, University of Southampton, comments: «This study highlights an important link between diabetes and osteoporosis, and identifies a selective deficit in skeletal development, which leads to excess fracture risk in this increasingly frequent disorder.

Professor Cyrus Cooper, Head of MRC Lifecourse Epidemiology Unit, University of Southampton comments: «Such international collaborations highlight the value of our unique cohort resources in revealing the causes and generating preventive strategies against musculoskeletal aging.»

Co-author Professor Nicholas Harvey, Professor of Rheumatology and Clinical Epidemiology at the MRC Lifecourse Epidemiology Unit, University of Southampton, added: «Babies» bones strengthen during the last stages of pregnancy.

Professor Nicholas Harvey, Professor of Rheumatology and Clinical Epidemiology at the MRC Lifecourse Epidemiology Unit, University of Southampton, led the study with Dr Elizabeth Curtis, Academic Clinical Fellow in Rheumatology.

Researchers at the Medical Research Council Lifecourse Epidemiology Unit, University of Southampton, undertook an analysis of the UK Clinical Practice Research Datalink database and calculated the risk of an individual experiencing a fracture.

Co-author Professor Cyrus Cooper, Professor of Rheumatology and Director of the MRC Lifecourse Epidemiology Unit, University of Southampton, says: «Our unit seeks to develop interventions to improve bone health early in life.

Professor Cyrus Cooper, Professor of Rheumatology and Director of the MRC Lifecourse Epidemiology Unit, University of Southampton, added: «This study forms part of a larger programme of work addressing risk factors for fracture across the lifecourse, and demonstrates the importance of the University of Southampton and MRC Lifecourse Epidemiology Unit in leading large, UK wide analyses on the internationally leading UK Clinical Practice Research Datalink dataset.

Professor Cyrus Cooper, Director of the MRC Lifecourse Epidemiology Unit, said: «This is a wonderful example of a biomedical discovery made by combining state of the art imaging methodologies with the world leading population science, for which Southampton has an established international reputation.»

Cyrus Cooper, Professor of Rheumatology and Director of the MRC LEU at the University of Southampton where the research was carried out, adds: «This study forms part of a larger programme of research at the MRC Lifecourse Epidemiology Unit at the University of Southampton.

Researchers from the Medical Research Council Lifecourse Epidemiology Unit (MRC LEU), University of Southampton have shed new light on how grip strength changes across the lifespan.

Professor Cyrus Cooper, Director of the MRC Lifecourse Epidemiology Unit and Professor of Rheumatology at the University of Southampton, says: «This is one of the first studies to use this technology to explore bone geometry, density and microstructure in patients with heart disease.

Dr. Julien Paccou, Clinical Research Fellow at the MRC Lifecourse Epidemiology Unit, University of Southampton, added: «In essence, this work and others show that people with a history of cardiovascular disease tend to have weaker bones.

Professor Keith Godfrey, from the Medical Research Council Lifecourse Epidemiology Unit and the National Institute for Health Research Southampton Biomedical Research Centre, and a member of the study team, said: «The new findings provide the first direct evidence linking faltering of a baby's growth in the womb with epigenetic modifications that themselves may increase the risk of childhood obesity.