Given their typical age of onset, a broad range of mental disorders are increasingly being understood as the result of aberrations of developmental processes that normally occur in the adolescent brain.4 — 6 Executive functioning, and its neurobiological substrate, the prefrontal cortex, matures during adolescence.5 The relatively late maturation of executive functioning is
adaptive in most cases, underpinning characteristic adolescent
behaviours such as social interaction, risk taking and sensation seeking which promote successful adult development and independence.6 However, in some cases it appears that the delayed maturation of prefrontal regulatory regions leads to the development of mental illness, with neurobiological studies indicating a broad deficit in executive functioning which precedes and underpins a range of psychopathology.7 A recent meta - analysis of neuroimaging studies focusing on a range of psychotic and non-psychotic mental illnesses found that grey matter loss in the dorsal anterior cingulate, and left and right insula, was common across diagnoses.8 In a healthy sample, this study also demonstrated that
lower grey matter in these regions was found to be associated with deficits in executive functioning performance.
Similarly, while impairments in
adaptive behaviour, and specifically daily living skills (DLS), are key areas of deficit in autism, some studies have reported a relationship between better DLS and
lower parenting stress (Tomanik et al. 2004; Green and Carter 2014) and others have found no association (Lecavalier et al. 2006; Estes et al. 2009, 2013; Peters - Scheffer et al. 2012).