The National
Lung Screening Trial (NLST) reported a reduction in lung cancer mortality in high - risk participants aged 55 to 74 who were randomly assigned to screening with low - dose computed tomography (LDCT) versus chest radiography.
National
Lung Screening Trial data presented to the National Institutes of Health confirmed that the test is cost effective — particularly compared to other screening programs.
Though the optimal scenario is actually estimated to catch fewer lung cancers than the criteria used in the National
Lung Screening Trial (NLST) in the US, the authors predict this more stringent scenario would require fewer CT scans, and lead to fewer false positive screens and lung cancer overdiagnosis, which can lead to patient harm.
Not exact matches
To identify the relevant mutations the scientists analyzed the blood samples of 1,858 men from three independent cohorts in Europe and North America: the Swiss arm of the European Randomized Study for Prostate Cancer
Screening, the large American
Screening trial, Prostate,
Lung, Colorectal, and Ovarian (PLCO), Princess Margaret Cancer Centre (University Health Network) and Mount Sinai Hospital (Sinai Health System) in Toronto.
For example, just before von Eschenbach arrived, NCI had agreed to fund a now - $ 350 million
screening trial to see if spiral computed tomography (CT) scans could detect
lung tumors missed by x-ray imaging in former smokers.
Wolin and colleagues analyzed data from a large, ongoing clinical
trial called the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial (P
trial called the Prostate,
Lung, Colorectal and Ovarian Cancer
Screening Trial (P
Trial (PLCO).
In the study about
lung cancer
screening via CT scan, more than 53,000 current or former heavy smokers — ages 55 to 74 — participated in the
trial.
The NPR story reported that another recent study found that the false - positive rate for
lung CT (computerized tomography) is 33 percent among those who have had two
screening tests — higher than the National Cancer Institute
trial found.