In a cross-sectional study, these researchers evaluated the responses to a socioeconomic questionnaire filled out by more than 530 patients who had undergone
lung transplantation in 2009 or 2010.
Not exact matches
What they found is that deaths
in the 90 days after an operation for
lung transplantation have gone down over the past 25 years from 19.4 % to 10 %.
But patients with the antibodies
in their blood are at high risk of dying while waiting for a perfect match, said Brian Feingold, M.D., M.S., study lead author and medical director of Pediatric Heart and Heart -
Lung Transplantation at Children's Hospital of Pittsburgh of UPMC and associate professor of the University of Pittsburgh School of Medicine
in Pennsylvania.
In the past five years, the number of
lung transplantations carried out has increased by about 20 %.
Other frequently occurring problems are airway complications, transplant failure, and other serious medical conditions — often elsewhere
in the body besides the
lungs — resulting from the
transplantation.
The Food and Drug Administration has issued a «Black Box» warning about the use of sirolimus
in lung transplant patients, at least when started at the time of
transplantation.
Trapnell and Suzuki were prompted to test the novel macrophage
transplantation therapy by studies showing that resident macrophage populations (such as those residing
in the
lung) can self - maintain without the cells having to regenerate directly from the bone marrow.
It is the first animal to hit a milestone, set nearly 20 years ago by the International Society of Heart and
Lung Transplantation, for determining whether a xenotransplantation approach is safe enough to try
in humans, Brenner notes.
In this study, Danny F. McAuley, Gerard F. Curley, Umar I. Hamid, John G. Laffey, Jason Abbott, David H. McKenna, Xiaohui Fang, Michael A. Matthay, and Jae W. Lee looked at whether
lungs that were rejected for
transplantation because of edema could be «reconditioned» to qualify for transplant.
Shorter adults are also more likely to be placed on mechanical ventilation while they wait for
lung transplantation, said lead author Jessica Sell, MPH, of the Columbia University Medical Center
in New York.
In light of the new findings, the researchers think current immune - suppression strategies should be re-evaluated in lung transplantatio
In light of the new findings, the researchers think current immune - suppression strategies should be re-evaluated
in lung transplantatio
in lung transplantation.
Returning to everyday life and resuming work
in one's regular occupation are common goals of transplant patients, yet not all who undergo
lung transplantation can go back to work.
Broadly suppressing the immune system after
lung transplantation may inadvertently encourage organ rejection, according to a new study
in mice.
Splitting his time between the Karolinska Institute and Kuban State Medical University
in Krasnodar, Russia, Macchiarini says he is now also engineering tissues of the
lung, heart, and other thoracic organs for
transplantation.
UT Southwestern was one of 16 medical centers across the country — and the only one
in Texas — participating
in a national clinical trial of the technology, which was aimed at significantly expanding the number of donor
lungs available for
transplantation.
Many technological innovations for diagnosis and treatment are expected to reach the clinic following validation, such as video - assisted thoracic surgery, sensitive imaging techniques, use of tracer gases, regenerative medicine (e.g.
in lung transplantation), nanoparticle - based carriers of inhalational drugs or bioactive compounds, personalised medicine (especially for
lung cancer), bronchoplasty, laser energy as a surgical tool, and metabolic imaging techniques.
Lung regeneration technologies may represent an alternative to
transplantation in the future.