Sentences with phrase «mapk signaling cascade»

Not exact matches

When mutated, BRAF, an enzyme that acts in a signaling cascade known as the MAPK / ERK pathway, becomes overactive and leads to increased cellular growth, a hallmark of cancer.
«Vegf sets off a signaling cascade that eventually activates a group of proteins, called Mitogen Activated Protein Kinases, or MAPKs,» said Gladstone Staff Scientist Joshua Wythe, PhD, the paper's lead author.
«Instead, the Vegf signaling cascade alerts only those MAPKs and ETS factors within the realm of Dll4 — assuring only the correct cells grow and differentiate over time to form arteries.»
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