Sentences with phrase «mcd diet feeding»
The mechanisms involved with liver fat accumulation on CD diets may be different from those at work during MCD diet feeding (11).
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When fed for equal lengths of time, HFD feeding results in 10-fold lower liver fat levels compared to what accumulates on an MCD diet (20).
In a follow - up study, Pickens et al. showed that despite inducing the same overall level of hepatic fat accumulation, fructose was more effective than glucose at inducing hepatocellular injury in mice fed MCD diets for 21 days (16).
Importantly, unlike human or other diet - induced rodent models of NAFLD, rodents fed MCD diets lose weight (due to a vastly lower caloric intake) and do not become insulin resistant (9, 19).
When both CD and MCD diets were fed to rats for 7 weeks, the MCD diet group had higher scores of liver inflammation and steatosis than the CD group.