Sentences with phrase «mmp activity»
Independent of MMP activity, TIMP - 1 can promote growth and inhibit apoptosis through various pathways, including P13K and PKA [9] and, furthermore, TIMP - 1 is able to provide β cell - specific pro-survival effects [5, 6, 10].
http://www.stemcellsportal.com/ Not exact matches
Sims» speech also sets out the ACCC's activities in relation to a number of areas of competition law (cartels, anti-competitive agreements and practices, MMP (noting the ACCC has «about» 10 in depth investigations underway)-RRB- and touches on the Harper Review and Murray Report as well as key issues surrounding privatisation, communications and water.
Excessive proteolytic activity of MMPs can be detrimental, leading to numerous pathological conditions, including blood brain barrier (BBB) / BSCB disruption after injury,» explains Tae Young Yune, PhD, of the Department of Biochemistry and Molecular Biology, School of Medicine, Kyung Hee University, Seoul, Korea.
The increase in MMP - 13 activity could be triggered by oxidative stress, which is also a hallmark of diabetic peripheral neuropathy.
In the research, Rieger treated the zebrafish with pharmacological agents that reduce MMP - 13 activity, with the result that skin defects were improved and chemotherapy - induced nerve damage was reversed.
They include its effects on endothelial cell «differentiation» to yield tubular - like structures, endothelial and tumor cell proliferation, apoptosis, and migration, as well as its effects on extracellular matrix remodelling enzyme activities of matrix metalloproteinase - 2 (MMP - 2) and urokinase - type plasminogen activator (uPA).
Our results in the zymographic assays for gelatinase and urokinase activities clearly showed that, in fact, kahweol was able to inhibit the expression of both MMP - 2 and uPA, identifying them as two relevant molecular targets for kahweol.
Since consumption of the Mediterranean diet is associated with decreased MMP - 9 activity [30], researchers must once again attempt to decipher the extent to which dietary benefits might be intertwined with intestinal microbiota.
In the period following a challenge with pathogenic intestinal microbes, MMP - 9 knockout mice show an increase in lactobacilli [24], meanwhile increased MMP - 9 activity is associated with intestinal permeability [25, 26], and the severity of human depression [27 — 29].