Further research based on autopsy specimens and animal experiments will be needed to clarify the relationship and determine if the patients with
MRI hyperintensity in their brains have symptoms.
Not exact matches
Authors examined the association between SVD and AD pathology by looking at magnetic resonance imaging (
MRI)- based microbleeds (MB), white matter
hyperintensities (WMH) and lacunes (which are measures for SVD) along with certain protein levels in cerebrospinal fluid (CSF) which reflect AD pathophysiology in patients with AD, VaD and healthy control patients.
Over time, «significant and persistent»
MRI abnormalities (called T1 - weighted signal
hyperintensities) developed in the brains of rats receiving the linear GBCA, gadodiamide.
However, in recent years, clinicians in Japan noticed that patients with a history of multiple administrations of Gd - CM showed areas of high intensity, or
hyperintensity, on
MRI in two brain regions: the dentate nucleus (DN) and globus pallidus (GP).
Dr. Kanda noted that because patients with multiple sclerosis tend to undergo numerous contrast - enhanced brain
MRI scans, the
hyperintensity of the DN seen in these patients may have more to do with the large cumulative gadolinium dose than the disease itself.
Dr. Kanda emphasized that there is currently no proof that gadolinium is responsible for
hyperintensity on brain
MRI.
Seven years later, the volume of white matter
hyperintensities was determined using brain
MRI.