8/27/2008 First Gene Associated with Dry
Macular Degeneration Found Findings indicate possible adverse consequences to new RNA therapies In a study that underscores the important role that individual genetic profiles will play in the development of new therapies for disease, a multi-institutional research team — led... More...
Not exact matches
One study
found that those with a high intake of carotenoids had a 43 % lower risk of age - related
macular degeneration compared to those with a low intake (37).
Lutein and zeaxanthin, two antioxidants
found in egg yolks, help prevent
macular degeneration, a leading cause of age - related blindness.
Researchers have
found that a diet enriched with omega - 3 helps repair and prevent retinal damage in mice, a discovery with potential for preventing blindness in premature infants and adults suffering from age - related
macular degeneration.
To
find the
macular degeneration gene, researchers compared DNA from people with and without the disease.
An unexpected
finding was that many of the innate immunity pathways that were active in the late stages of these inherited blinding diseases were the same as those that are associated with more common vision disorders including diabetic retinopathy and age - related
macular degeneration, or AMD.
«We were surprised to
find so many similarities between these two diseases, but most striking was that some of these common signatures are shared with other conditions like diabetic retinopathy and age - related
macular degeneration,» said William A. Beltran, senior author on the study, an associate professor of ophthalmology in Penn Vet's Department of Clinical Sciences and Advanced Medicine and director of the Division of Experimental Retinal Therapies.
The
findings, published in JAMA Ophthalmology, point to critical interventions in the prevention and treatment of blinding eye diseases, such as age - related
macular degeneration and diabetic retinopathy (DR), among Chinese Americans.
The
finding could help explain why eyesight degenerates with age — and in diseases such as
macular degeneration and diabetes.
The
finding could lead to the development of new drugs for wet
macular degeneration and diabetic
macular edema.
The
findings of the Mainz researchers thus contradict the current assumption that age - related
macular degeneration only occurs in the section of the population that is over 50 years old.
Central visual field loss, a scotoma or blind area in central vision, is
found most commonly in patients with age - related
macular degeneration (AMD).
«We
found that intensive doses of statins carry the potential for clearing up the lipid debris that can lead to vision impairment in a subset of patients with
macular degeneration,» said Joan W. Miller, M.D., the Henry Willard Williams Professor and Chair of Ophthalmology at Harvard Medical School and Chief of Ophthalmology at Massachusetts Eye and Ear and Massachusetts General Hospital.
«Our
findings are a promising step towards image - guided prediction of the progression of age - related
macular degeneration.
That biotech company may cure
macular degeneration someday — I hope they do because I got stock options — but what I really want to do is
find stuff out.
Such light therapy might
find applications in people who accidentally ingest methanol or who suffer from other forms of acquired blindness, such as age - related
macular degeneration and glaucoma, says Janis T. Eells of the Medical College of Wisconsin in Milwaukee.
SALT LAKE CITY — Two major eye diseases and leading causes of blindness — age - related
macular degeneration and diabetic retinopathy — can be reversed or even prevented by drugs that activate a protein
found in...
Our
findings open the way to develop therapeutic strategies to remove lipofuscin from RPE cells, which may have implications for the treatment of age - related
macular degeneration in which lipofuscin accumulation in cells is a causative factor.
These
findings suggest that RPE cells, derived from iPS cells, could be used to treat blindness in humans, such as blindness caused by age - related
macular degeneration, a leading cause of blindness in the Western world.
No significant relationship was
found between vitamin D status and early or advanced age - related
macular degeneration after making adjustments for age and other known age - related
macular degeneration risk factors.
Because Age Related
Macular Degeneration comes from the breaking down of retinal cells, the vitamins and nutrients which have been
found to protect eyes from AMD are aiding the body by keeping the eyes healthy and improving eyesight.
The National Eye Institute's Age - Related Eye Disease Study (AREDS)
found that taking a specific high dose formula of antioxidants and zinc may delay or prevent intermediate age - related
macular degeneration from progressing to the advanced stage.
Harvard researchers
found at least a 34 % decreased risk of age - related
macular degeneration for women aged 40 and older who supplemented with 1,000 micrograms of B12.
Additionally, beta carotene
found in carrots helps prevent
macular degeneration and formation of cataracts as you age.
A Cochrane database system review in 2012
found that there was no evidence that multivitamin supplements could prevent age - related
macular degeneration (20).
One study in 356 middle - aged and elderly people
found a 43 % reduction in the risk of
macular degeneration among those with the highest intake of carotenoids, especially lutein and zeaxanthin, compared to those with the lowest intake (45).
Also, a 2009 National Eye Institute (NEI) study that used data obtained from the Age - Related Eye Disease Study (AREDS)
found participants who reported the highest level of omega - 3 fatty acids in their diet were 30 percent less likely than their peers to develop
macular degeneration during a 12 - year period.
Lutein and zeaxanthin, phytonutrients protective against cataracts and
macular degeneration, can be
found in high levels in kale, collard greens, and carrots.
A 2013 study from the American Journal of Clinical Nutrition
found subjects who took vitamin B - 12 and folate supplements had significantly lower incidences of age - related
macular degeneration (AMD) ten years later.
I have wet
macular degeneration in one eye (thank goodness for one good eye) and may eventually
find it easier to read using an ereader.
However, having developed
macular degeneration, I
find I can no longer read my printed treasures... the sole and only reason for my existence!
Whether it is
macular degeneration which slowly and incurably blinds the patient, or Parkinson's disease that causes uncontrollable tremors that make reading a book nearly impossible, e-readers may be the necessary tool to bringing the patient back to some of the joy they
found in reading.
Several studies performed on various animals have also
found that beta - carotene seems to protect against the leading causes of blindness,
macular degeneration and cataracts.
VisionWalk is a family friendly event designed to raise awareness and dollars in support of Foundation funded cutting - edge research to
find the preventions, treatments, and cures of retinal degenerative diseases such as retinitis pigmentosa, usher syndrome, Stargardts, and
macular degeneration.
Cutting - edge research also may have
found another way to tackle the wet form of
macular degeneration.
Cost - effectiveness of ranibizumab and bevacizumab for age - related
macular degeneration: 2 - year
findings from the IVAN randomised trial