Sentences with phrase «mammary tumours»

(C) Combined data for the growth of mammary tumours in Slc6a14 + / + / PyMT (WT) mice and Slc6a14 − / − / PyMT (KO) mice; data are means ± S.E.M. for all mammary glands in eight mice in each group.

A similar approach was used for the analysis of mammary tumours in MMTV / Neu - Tg female mice on Slc6a14 + / + and Slc6a14 − / − backgrounds.

PyMT - Tg (Polyoma middle T oncogene - transgenic) mice and MMTV / Neu - Tg (mouse mammary tumour virus promoter - Neu - transgenic) mice were from Jackson Laboratories.

However, when crossed with PyMT - Tg mice or MMTV / Neu (mouse mammary tumour virus promoter - Neu)- Tg mice, the development and progression of breast cancer were markedly decreased on Slc6a14 − / − background.

The studies reported in the present study demonstrate that Slc6a14 plays an important role in promoting the development and growth of PyMT - driven and Neu - driven mammary tumours in mice.

Factors influencing the incidence and prognosis of canine mammary tumours.

(D) Deletion of Slc6a14 delays the development and growth of mammary tumours also in MMTV - Neu - Tg mice.

There are many health benefits associated with spaying your female dog, such as decreased chances of developing mammary tumours, uterine infections, and even hair coat problems.

Mammary tumours from PyMT / Slc6a14 + / + and PyMT / Slc6a14 − / − mice were preserved in 10 % buffered formalin.

We then monitored mammary tumour incidence and progression in this mouse line on Slc6a14 + / + and Slc6a14 − / − genetic backgrounds.

We also performed microarray analysis of PyMT - Slc6a14 + / + and PyMT - Slc6a14 − / − mammary tumours to evaluate the expression of amino acid transporters without any biased preconception of the identity of the transporters that might be subject to changes in expression in association with Slc6a14 deletion.

Although mice completely lacking SLC6A14 are viable and exhibit normal mammary gland development, these animals are highly resistant to mammary tumour initiation and progression driven by potent oncogenes.

In contrast, no Slc6a14 − / − female with PyMT transgene developed tumours at 3 months of age; however, at 4 months of age, small tumour nodules became detectable (Figure 2B), indicating a marked delay in mammary tumour development in PyMT - Tg mice as a consequence of Slc6a14 deletion.

She had lumps, scars, bad hips, tumours, a mouthful of rotten teeth and a large mammary tumour.

** There is a current research project being carried out by the Animal Health Trust into Mammary Tumours in the English Springer Spaniel.

Accessing the canine tissue archive at the Institute of Veterinary Pathology located at the Animal Hospital, the study's researchers analysed the surrounding tissue of dogs mammary tumours using molecular biology and immunohistological methods.

Influence of ovariectomy at the time of mastectomy on the prognosis for canine malignant mammary tumours.

Therefore, we expected that PyMT - driven mammary tumours in Slc6a14 − / − mice would exhibit a decrease in cell proliferation, mTOR signalling and HIF1α.

In the present study, we interrogated the role of this transporter in breast cancer by deleting Slc6a14 in mice and monitoring the consequences of this deletion in models of spontaneous breast cancer (Polyoma middle T oncogene - transgenic mouse and mouse mammary tumour virus promoter - Neu - transgenic mouse).

We also evaluated the consequences of Slc6a14 deletion in breast cancer development and growth in another model of spontaneous mammary tumour (MMTV - Neu - Tg mouse).

The chance of contracting some infectious cat diseases will be reduced, as will the likelihood of developing mammary tumours (breast cancers), pyometra (life threatening womb infections), testicular cancer, and many other illnesses.

Maybe the answer lies with the mouse mammary tumour virus

PDGFR - α, PDGFR - β, VEGFR - 2 and CD117 expression in canine mammary tumours and evaluation of the in vitro effects of toceranib phosphate in neoplastic mammary cell lines

De-sexing helps prevent problems such as roaming, aggression and prostatic enlargement in males, and mammary tumours in females.

As I understand it the incidence of mammary tumours is high in entire bitches, and testicular cancer in entire males is pretty rare.

(A) Demonstration of Slc6a14 mRNA up - regulation in PyMT - driven mammary tumours in mice; N, mammary tissue from wild - type mice; T, mammary tumour tissue from PyMT - Tg mice.

Fewer cats developing pyometras, mammary tumours, mammary hyperplasia etc or needing Caesarean sections

Your pet will no longer have seasons, future life threatening diseases of the womb such as pyometra and cancer will be prevented and the risk of mammary tumours will be very much reduced.

Female dogs may develop hardening of the mammary glands, a condition known as mammary cancer or mammary tumour.

Unspayed females are more prone to infections of the womb and also mammary tumours than are spayed females.

Neutered cats are at reduced risk from Feline Leukaemia Virus (FeLV), Feline Immunodeficiency Virus (FIV), mammary tumours (females), pyometria (womb infections) and injuries 1.