Sentences with phrase «many diseases of aging»
As in, yes you can buy into a private plan at age 60 for example, but it will be very expensive and you'd better pray they don't come up with an exclusion if a disease of age catches up with you.
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Their focus on creating solutions to the diseases of aging, one of the greatest problems facing humanity, is very much in line with my goal to positively impact the lives of millions of people around the world.»
Mike Kope, CEO at SENS, said of Buterin's charity, «SENS Research Foundation is honored to be the recipient of Vitalik's incredible generosity... His support is critical to SENS Research Foundation's expansion of our programs... Our work to cure the diseases of aging is dependent on the generous support of our donors and we appreciate his support tremendously.»
Brisbane, California - based Unity Biotechnology Inc , a developer of treatments that prevent, halt, or reverse numerous diseases of aging, has raised...
They are most likely to talk of a great increase in average life expectancy, of the conquest of the diseases of aging, and of preserving the capacities and vigor of youth.
We know that exercise can reduce the risk of heart disease, certain cancers, dementia, and other diseases of aging.
Instead, they are suffering from the so - called diseases of aging that are really diseases of inactivity and overeating.
We need to outlive the diseases of aging.
«To form a protective wall against the unhealthy predominance of the emotional side against that feeble sensitiveness — the disease of our age, which must be recognized as the usual reason for the increasing frequency of depression, mental illness, and suicide.»
Albany Medical Center's Alzheimer's Center Director Dr. Earl Zimmerman joins Alan in the studio to discuss Alzheimers, dementia, and other neurological diseases of aging.
Even more than other types of cancer, melanoma is a disease of aging, with older patients more frequently diagnosed with the disease and having a worse prognosis.
Although cancer certainly can and does strike young people, it is, by and large, a disease of aging — and the leading cause of death in Americans between 60 and 79 years old.
If the genetic mutation that gives people with Laron syndrome their short stature also protects them against two of the most pernicious diseases of aging, diabetes and cancer, then it prompts two obvious questions: What other diseases might the mutation protect against, and do people who carry the mutation in fact live longer than their unaffected peers?
«AF is a disease of aging and it is common, costly and has lots of complications,» Soliman said.
Caloric restriction became something of a fad two decades ago, when a few individuals set out to cut their calories by 30 percent to slow the diseases of aging, but the Wisconsin and NIA studies have a much broader focus.
In all species where it has been shown to delay aging and the diseases of aging, it affects the regulation of energy and the ability of cells and the organism to respond to changes in the environment as they age.»
That was going much too far, because cancer is also a disease of aging: Its incidence increases steadily with age.
«GSK is betting that we have discovered a whole new class of drugs that will treat all or many diseases of aging at once,» says Christoph Westphal, CEO and cofounder of Sirtris.
Uncontrolled calcium signaling and ROS in the mitochondria is behind a number of common diseases, such as stroke or heart attack, and is thought to play a role in diseases of aging such as neurodegenerative disease.
«The research is really to prevent the chronic debilitating diseases of aging,» says Nir Barzilai, a molecular geneticist and director of the Institute for Aging Research at the Albert Einstein College of Medicine in New York.
Yet one - third of global health issues are related to neurological problems, such as depression, pain, and the diseases of the aging brain.
Work at the institute focuses on disorders of the developing brain, such as autism and attention deficit disorder; diseases of the aging brain, including Alzheimer's and Parkinson's; and restoring function to the damaged brain, including brain - machine interfaces and deep brain stimulation.
The programs also seek to integrate neuroscience and clinical disciplines with public health initiatives in order to disseminate and implement novel findings from research centers of excellence, as well as conduct community outreach to raise awareness about the diseases of aging.
NPT088 utilizes NeuroPhage's novel and proprietary GAIM (General Amyloid Interaction Motif) technology to simultaneously target multiple types of misfolded proteins found in many diseases of aging, including Alzheimer's and Parkinson's diseases, as well as peripheral diseases, including the systemic amyloidoses.
Alzheimer - type dementia is a common chronic disorder, becoming even more prevalent as the population ages, and it frequently coexists with other diseases of aging.
In recent years, researchers have developed so - called «senolytic» drugs that wipe out senescent cells in aging mice and mouse models of age - related disease, exploiting the high dependence of these cells on specific biochemical survival pathways.9, 10 In these studies, senolytic drugs have restored exercise capacity9 and formation of new blood and immune precursor cells11 in aging mice to near youthful norms, and prevented or treated mouse models of diseases of aging like osteoarthritis, 12 fibrotic lung disease, 13 hair loss, 14 atherosclerosis, 15,16 and age - related diseases of the heart itself.9 UNITY Biotechnology is leading a growing charge toward the clinic, with human clinical trials expected to begin in 2019.
UNITY Biotechnology Announces Extension of Series B Financing Bringing Total Round to $ 151 Million August 17, 2017 SAN FRANCISCO, August 17, 2017 / PRNewswire / — UNITY Biotechnology, Inc. («UNITY»), a privately held biotechnology company creating therapeutics that prevent, halt, or reverse numerous diseases of aging, today announced the closing of an additional $ 35 million in Series B financing.
His lab is collaborating with other Buck labs to evaluate the role of the mitochondria in aging and in such diseases of aging as cancer, diabetes, Parkinson's, Alzheimer's and Huntington's.
The goal for the near future is to align ever more of the research community and its funding institutions with this goal, and make real progress towards bringing an end to the pain, suffering, and disease of aging.
Telomere length predicts both cellular health and disease in rodent models and humans.8 Shorter telomeres predict onset of cardiometabolic diseases of aging.9 Chronic stress is associated with higher inflammation, shorter telomeres, and lower activity levels of telomerase, the cellular enzyme that elongates telomeric DNA.10, 11 Levels of amyloid beta (Aβ) proteins circulating in the blood appear to be stress - related in rodent models12 and may be affected by stress reduction, and greater Aβ42 / Aβ40 ratios are associated with lower risk of dementia.13
Because neurodegenerative disorders like PD are largely diseases of aging, modeling them in a culture dish using neurons grown from iPS cells has been thought to be exceedingly difficult, if not impossible.
Recent genetic research in humans has implicated mutations in the gene for Tet2 as a risk factor for many different diseases of aging, including cancer, cardiovascular disease, and stroke.
Parkinson's disease (PD) is a neurodegenerative disease of aging, whose most obvious symptoms — tremors, gait disorders, and a «mask - like» facial appearance — involve the loss of fine motion control.
BIIB054 was originally developed by biotech company Neurimmune, using a platform they call Reverse Translational Medicine (RTM ®), which derives therapeutic antibody candidates from libraries of de-identified B - cells isolated from ostensibly healthy older adults (those free of specific neurological diseases of aging).
Following a period of intensive meditation, genes involved with the infectious cycle may get downregulated along with related host genes regulating protein synthesis, an explanation that is supported by other stress reduction interventions that have shown increased innate antiviral activity, such as upregulated Type 1 interferon activity.40 Shorter telomeres in population - based studies have been predictive of earlier onset of chronic diseases of aging, including diabetes, 41 cardiovascular disease9 and certain cancers.42
UNITY Biotechnology Appoints Additional Biotech Industry Veterans to Executive Team September 21, 2017 SAN FRANCISCO, Sept. 21, 2017 / PRNewswire / — UNITY Biotechnology, Inc. («UNITY»), a privately held biotechnology company creating therapeutics that prevent, halt, or reverse numerous diseases of aging, today announced recent additions to its executive team.
Completes $ 55 Million Series C Financing March 19, 2018 SAN FRANCISCO, March 19, 2018 / PRNewswire / — UNITY Biotechnology, Inc. («UNITY»), a privately held biotechnology company developing therapeutics to slow, halt or reverse diseases of aging, today announced the closing of a $ 55 million Series C financing.
These findings are entirely in line witht the known etiopathogenesis of the neurodegenerative diseases of aging.
However, should it turn out to be operationally impossible to maintain such a distinction where it matters (e.g. in the human case), then the very concept of a disease of aging is called into question.
The long - term goal of this project is to understand how these modifications are regulated by the NAD + - dependent sirtuin deacylases and their influence on the diseases of aging.
The aging brain has a decreased ability to lay down new memories, and this decrease is exacerbated in diseases of aging such as stroke and Alzheimer's disease.
Current research on aging has largely focused the molecular mechanisms of age - related diseases, and mitochondrial dysfunction has been associated with several human diseases of aging.
He says that his immediate and long - term research goals are to «identify and therapeutically target metabolic pathways that regulate energy balance in the context of obesity, diabetes, cancer, and the chronic diseases of aging.»
Erosion of telomeres has long been associated with diseases of aging, but how telomere length affects human disease has remained largely a mystery.
Finally, we need new approaches to restoring a normal lifespan to those who are HIV - positive, and dying much too early from diseases of aging.
SENS Research Foundation is a 501 (c)(3) nonprofit that works to research, develop, and promote comprehensive regenerative medicine solutions for the diseases of aging.
«Because late - onset Alzheimer's is a disease of age, many physiologic changes with age may contribute to risk for the disease, including changes in bioenergetics and metabolism.»
Some experts suspect that chemo may also lessen the inflammation associated with osteoarthritis, which is typically considered a disease of aging but may prove to be linked to immune system problems, too.
Bioidentical Hormones prevent or reverse the degenerative diseases of aging, directly competing with the profits of the drug industry, thereby explaining the animosity and information warfare between the drug industry and bioidentical hormones.
Without this hormone message which turns on DNA expression of protein synthesis, we lack the reparative and regenerative proteins needed to prevent the degenerative diseases of aging.