Sentences with phrase «many of these affected dogs»

«This regenerative technology, termed AAV gene transfer, provided long - lasting benefit to the entire musculature of affected dogs that would have otherwise perished, extending a healthy lifespan for more than 4 years,» said Dr. Martin Childers, senior author of the Muscle & Nerve study and a UW Medicine researcher in Seattle.

Four collaborating research groups in the United States and France found a way to safely replace the disease - causing MTM gene with a healthy gene throughout the entire musculature of affected dogs.

In other words, copper toxicosis results from the inability of the affected dog to mobilise and excrete dietary copper which is surplus to its requirements.

There does not appear to be any significant difference in the incidence of the condition in relation to the sex of the affected dogs.

First it will be necessary to formally exclude the COMMD1 gene by sequencing all of COMMD1 in a small number of affected dogs that are known to not carry the COMMD1 deletion to ensure there is not a second mutation in the same gene.

Almost no information exists concerning the survival time of affected dogs, if they were treated and which treatment had been chosen and at last their cause of death.

MRI and other diagnostic modalities have demonstrated actual structural differences in the brains of affected dogs that appear analogous to the structural changes in affected human brains.

We have designed a survey which is directed to owners of affected dogs, but can also be filled in by veterinarians if the owner is unavailable or does not want to participate.

Ten years is the average age of affected dogs.

Radiation therapy can help extend the lives of affected dogs, but also is ineffective against tumor cells that have metastasized.

CAV - 2 also produces pneumonia in 10 - 20 percent of the affected dogs.

Although great strides have been made in identifying genetic markers and developing screening tests for many gene - based diseases, there are no test yet for PLN, PLE, or RD. Therefore, the breed club's health committee recommends that close relatives of dogs with these diseases not be bred and that periodic tests be done on the relatives of affected dogs to determine if the disease is present and help establish a baseline for research.

Many of these affected dogs are older in age; however, dog arthritis can also transpire in any age, breed, and health condition.

Because eating small amounts of aflatoxins over a period of time will cause cumulative liver damage or cancerous tumors, a very small percentage of affected dogs would be reported,.

Fortunately, the vision of affected dogs can often be restored to a normal state by surgically removing the abnormal lens and substituting an artificial lens in its place.

Another important fact to remember is to avoid breeding your dog — given the genetic component of this disease, spaying or neutering of affected dogs can at least prevent the disease being passed on.

In terms of numbers of affected dogs reported, temperament problems were the most frequent.

First - step relatives (parents, full and half siblings, and offspring if any) of affected dogs who will be used for breeding should be tested.

The parents and full and half siblings of an affected dog should not be bred close on the pedigree that produced it and should be bred to mates that do not have a family history of iris coloboma.

The nose of an affected dog appears thickened, because of the accumulation of horn - like dead tissue.

Breed carriers (parents of affected dogs or those with one mutation) only to clear - tested mates.

Heartworm in pets is a serious and potentially fatal disease that is caused by foot long worms (heartworms) that live in the heart, lungs, and associated blood vessels of affected dogs and cats.

Approximately 60 % of affected dogs have degeneration of the mitral valve, 30 % have degeneration of both the tricuspid and mitral valves, and the remaining 10 % have degeneration in the tricuspid valve only.

Most allergies appear after the pet is six months of age with the majority of affected dogs over age two.

Canine soft - tissue sarcomas are common and while many are easily treated, the disease can spread and become deadly to about one - third of affected dogs.

In addition, don't breed offspring or littermates of affected dogs.

Approximately 60 % of affected dogs have degeneration of the mitral valve, 30 % have lesions in both the tricuspid and mitral valve leaflets, and 10 % have only tricuspid valve disease.

Two different forms of cushings disease in dogs, the spectrum of clinical signs and the behavior of affected dogs makes Cushing's disease hard to diagnose.

This means any affected animal has two parents which are either affected or carriers, and that at least half of an affected dogs littermates are probably carriers.

According to Woodhaven Labs dogs that have been afflicted have a one in three chance of a re-occurrence and a small percentage of affected dogs may experience permanent damage showing signs of a distorted tail posture.

That means, both parents of an affected dog must have at least one copy of the mutation and both parents must have passed a copy of the mutation to the offspring.

Lyme disease is one of the most common tick - transmitted diseases in the world but only causes symptoms in 5 % -10 % of affected dogs.

First - step relatives of affected dogs (parents, full and half siblings, and offspring) should be bred only to mates with pedigrees as clear of lymphoma as possible and who have no affected close relatives.

In a large retrospective study, the mean age of affected dogs at the time of diagnosis was found to be 8.6 years (range 4.5 - 14.5 years).

75 % of affected dogs will improve to some extent while they're taking this drug.

A simple dominant mode of inheritance can be excluded because the vast majority of affected dogs were born to clinically normal parents.

Phenobarbital was by far the most commonly used drug for amelioration of the seizures, with 30.8 % of all affected dogs receiving this drug.

Of the affected dogs that died, 62 % succumbed to disorders of quality of life issues directly attributable to idiopathic epilepsy.

Only 3 of the affected dogs had an affected parent, and breedings between an affected and an unaffected parent could produce either all unaffected offspring or a mix of affected and unaffected offspring in the same litter.

Many of the affected dogs will have chronic recurrent pneumonia, which as most owners / breeders know is not readily apparent to the «untrained eye.»

In 22.6 % of the affected dogs, the seizures occurred both during sleep and while awake.

Fatalities have only been reported with the onset of pneumonia, but the rate is less than 10 % of affected dogs.

Conventional maintenance therapy of phenobarbital, potassium bromide, clorazepate, dilantin or diazepam was used alone or in combination for the majority of affected dogs.

A relatively large number of the affected dogs (36.6 %) were not receiving any medication.

Six of the affected dogs began with mild generalized seizures that progressed to grand mal seizures over the course of their disease.

Each affected dog has at least one affected parent, but it can be expected that half of the offspring of an affected dog will be free of the defective gene.

The major observation made from examining the pedigree was that the vast majority of affected dogs were born to healthy parents (143 affected dogs from 112 litters).

A GoFundMe was set up to help the foster mom of the affected dogs pay for medical treatment.

CD can be diagnosed in the early weeks of the affected dog's life.

The underlying aim of the Glasgow study was to improve the clinical knowledge of CDRM by regularly examining a large group of affected dogs.