Sentences with phrase «many vaccine approaches»

Many vaccine approaches have shown promise in being able to protect nonhuman primates against Ebola Zaire.

«This particular vaccine approach didn't work, but there are lots of different vaccine approaches in testing that produce different immune responses,» Buchbinder says.

The company's vaccine approach in both cases is to use viruslike particles (VLPs) containing surface proteins that make the VLPs resemble a virus, thereby eliciting the proper immune response — even though the VLPs lack the genes needed to replicate themselves.

Three vaccine approaches have been shown to protect monkeys against Zika infection, and human trials began in July.

Some researchers remain skeptical of the vaccine approach because it doesn't treat the underlying physiology of addiction.

They will also work with Vir Biotechnology, Inc. of San Francisco, which has licensed aspects of their CMV - based vaccine approach, to expand testing with plans to start a human clinical trial in 2020.

Federoff believes that this vaccine approach might work to treat people who contract variant Creutzfeldt - Jakob disease (vCJD), a currently incurable human form of prion disease, related to mad cow disease (BSE).

The mRNA vaccine approach has other advantages, Weissman added: «If a vaccine is effective after just a single immunization, the infrastructure needed for its administration can be much simpler.

Scientists have debated the mechanism of action of captagon, and Janda's vaccine approach has been useful in dissecting how the components of the drug exert their psychoactive effects.

«This broad implication is in contrast to a more traditional vaccine - based approach, which requires a specialist to surgically remove tumor samples from a patient's body then create a personalized vaccine approach for one specific patient.»

Concepts of how to apply vaccines as part of cancer treatment or as prevention of recurrence, are moving vaccines from being considered a secondary player in cancer clinical management to vaccine approaches gravitating towards becoming a central plank in the newest area of cancer therapy research.

The second focus on my research is the development of novel therapeutic vaccine approaches for cancer.

Uniquely it focuses both on diseases of humans and livestock and tests new vaccine approaches in parallel in different species.

Douglas J. Schwartzentruber and colleagues at The University of Texas MD Anderson Cancer Center demonstrate that patients with metastatic melanoma receiving high doses of interleukin - 2 (IL - 2) plus a gp100 peptide vaccine had significant improvement in overall clinical response, providing further validation for vaccine approaches to cancer treatment.

At the end of his talk, Coukos turned his attention to a dendritic cell vaccine approach in combination with a VEGF - targeting antibody and chemotherapy.

Today, two AS aggregate - clearing immunotherapies have advanced into human testing, with one using an active vaccine approach and the other a passive mAb infusion strategy.

He has made several important contributions in this area including identifying a new strain of CHIKV virus, identification of host cellular targets of HIV accessory genes, new novel DNA vaccine approaches for HIV, CHIKV, RSV, Dengue, MERS and Zika among others.

Steven Russell, M.D., Ph.D., of the Mayo Clinic, and John Bell, Ph.D., of the University of Ottawa in Canada, each presented talks on how oncolytic viruses could be combined with vaccine approaches to produce more powerful results than vaccines alone.

The HVTN maintains a vigorous program to facilitate the development of novel vaccine approaches.

Zoetis continues work with Iowa State University on a second vaccine approach to help control PEDv.

The novel vaccine approach also may have applications beyond rabies, particularly in developing a vaccine against white - nose syndrome, a disease that is decimating bat colonies around the country.

Many of the current cancer researchers are investigating ways of stimulating the immune system to recognize the cancer cells specifically and selectively, for example by a vaccine approach (See also «Gene Therapy» below).

Not exact matches

Doctors argue this vaccine's noninterference with other treatments is crucial, because curbing the opioid crisis will require a multifaceted approach.

We work with partners to provide effective vaccines, drugs, and diagnostics and to develop innovative approaches to deliver health services to those who need it most.

The National Institute on Drug Abuse is pursuing a mix of approaches that include developing non-opioid pain medicines, conducting research on vaccines that may blunt the impact of fentanyl and its related offshoots, getting public health organizations to increase the availability and use of medications already available to treat opioid addiction and getting medications such as buprenorphine and naloxone, which suppress withdrawal symptoms and ease cravings, into the hands emergency room doctors dealing with patients with opioid addictions.

«What that suggests is that this approach really gives us broad spectrum protection, and could serve as a basis for an effective pre-pandemic vaccine.»

At the end of the 1980s and during the early 1990s we started thinking that a new approach that proved successful might lead to a universal vaccine.

«We approach vaccine targets from a virus family perspective,» Young said.

To fund the new approach to the work, tenOever contacted the Army Research Office, which sponsors new technology for vaccine development.

«One day we may be able to tailor vaccines to individual children instead of taking a one - size - fits - all approach, and thus reduce risks even further,» he says.

«And so if you're in the vaccine community, what's the best approach to this?

Researchers for the past decade have focused on the T cell approach, based on studies showing that monkeys receiving such vaccines against simian immunodeficiency virus, related to HIV, lived longer or had lower viral levels than usual.

Vaccines 2.0 Rather than take Han's broader approach, Stanford University's Mark Davis, director of the Institute for Immunity, Transplantation and Infection, is focusing on unraveling one specific piece of the puzzle: the immune response to flu vaccination.

«We think we can use our molecular, rational design approaches to make a better flu vaccine for people who really need it,» says study leader Andrew Pekosz, PhD, an associate professor in the Department of Molecular Microbiology and Immunology at the Bloomberg School of Public Health.

The company claims its VLP approach allows it to manufacture a vaccine to match a particular virus strain in about three months.

Throughout the company's trials the FDA has been on alert for signs that a patient could have a bad reaction as a result of this vaccine - making approach.

University of Queensland researchers have developed a world - first vaccine - style therapeutic approach to treat rheumatoid arthritis, a debilitating disease affecting more than 450,000 people in Australia.

The advantage of Novavax's approach is that a vaccine can be made rapidly and in high volume, compared with the egg - based approach that's used today, says Ted Ross, an associate professor of microbiology and molecular genetics at the University of Pittsburgh's Center for Vaccine Researchvaccine can be made rapidly and in high volume, compared with the egg - based approach that's used today, says Ted Ross, an associate professor of microbiology and molecular genetics at the University of Pittsburgh's Center for Vaccine ResearchVaccine Research (CVR).

Other experimental vaccines take a different approach.

Subramanian says that an optimal approach may be to strategically use universal vaccines alongside conventional vaccines to protect at - risk groups while controlling transmission in the whole population.

Are «elite controllers» the key to understanding HIV infection — and do their immune systems offer a new approach to developing an AIDS vaccine?

A series of vaccine and microbicide clinical trials to prevent HIV transmission have been unsuccessful, and scientists are returning to the drawing board to devise new approaches.

The success of both vaccines thus far in stringent monkey models has led Picker and his colleagues to believe their CMV - based approach to making vaccines has the potential to be engineered to tackle a variety of infectious diseases.

China has not approached the WHO about the trial but the WHO says it has been kept informed by United Biomedical, and has seen the results from animal tests of the vaccine.

In the end, a vaccine will probably need to take multiple approaches at once, like combination therapy against cancer, says Jeffery Taubenberger of the National Institute of Allergy and Infectious Diseases.

The Gates Foundation has bet on vaccines, but is also funding less conventional scientific approaches.

Other scientists are using multi-omic approaches for preventive medicine, for example, to be more effective and efficient in vaccine development.

A new approach to the live flu vaccine would be particularly advantageous right now after the Centers for Disease Control and Prevention stopped recommending use of the live attenuate flu vaccine, FluMist ® earlier this year.

In the battle against multidrug resistance, the ideal way of preventing disease is a vaccine, and having a structure of BamE opens the door to a structural vaccinology approach.»

«This study has changed our approach to developing a universal flu vaccine,» said corresponding author Maureen McGargill, Ph.D., an assistant member of the St. Jude Department of Immunology.