Sentences with phrase «median survival time in»

«We increased median survival time in animals by 40 %, which gives us enough evidence to go on to human clinical trials,» Belcher says.

Not exact matches

Brahmer emphasizes that the relatively small increase in median survival time with the use of the new immunotherapy drugs may be somewhat misleading in terms of overall impact of the medicines.
A follow - up of the 48 patients who were evaluable at a median time of 24 months indicated no statistical differences between the two groups in terms of overall or progression - free survival.
Of the dogs stricken with osteosarcoma, 35 had the cancer in a leg which was subsequently amputated, followed by chemotherapy, which is the standard - of - care treatment; the dogs with elevated total cholesterol had a median survival time of 455 days, more than 200 days greater than the median survival time for dogs with normal cholesterol.
The team found that patients with more varied types of bacteria in their digestive tract had longer median progression - free survival, defined at the time point where half of studied patients have their disease progress.
The researchers then tested their scoring method using data on 688 AML patients in three different clinical trials, In each of these groups, patients with low scores (methylation patterns similar to normal HSCs) had approximately twice the median survival time of patients with high scorein three different clinical trials, In each of these groups, patients with low scores (methylation patterns similar to normal HSCs) had approximately twice the median survival time of patients with high scoreIn each of these groups, patients with low scores (methylation patterns similar to normal HSCs) had approximately twice the median survival time of patients with high scores.
Those that got Photofrin either intravenously or encapsulated in nanoparticles had a median survival time of 13 days.
Sweeney said more time is needed to assess the benefit of the drug combination in the men with lesser burdens of disease, as their median survival has not yet been reached.
The tumors grew rapidly in the control experiments (the median time for tumor - free survival was one week) and any differences in tumor - free survival for the controls and the mice injected with cells expressing mutated PREX2 were not statistically significant (Horrigan et al., 2017).
Although researchers found that delivering the Isis drug directly into the brain nearly doubled survival time in a mouse model of SMA3, systemic administration in the rodents — which usually die within two weeks — has been shown to extend median survival by up to eight months.
Median overall survival, commonly referred to as median OS, is the time point at which 50 % of patients in a trial are expected to have surMedian overall survival, commonly referred to as median OS, is the time point at which 50 % of patients in a trial are expected to have surmedian OS, is the time point at which 50 % of patients in a trial are expected to have survived.
When that number is over 70 mg / dL, the median survival time of the 24 dogs in one study was, unfortunately, only 30 days.
In one study, median survival time was 118 days for dogs with evidence of tumor invasion of other local organs compared with 218 days for dogs with no evidence of invasion beyond the urinary bladder.
In general, dogs with meningiomas have a median survival time of 1 - 2 years.
Dogs in the standard - dose and low - dose pimobendan groups had significantly longer median survival times than dogs in the conventional group (334, 277 and 136 days, respectively; P < 0.001).
According to the Ohio State University Veterinary Medical Center's webpage on mammary cancer, cats with tumors more than 3 cm in diameter have a median survival time of 4 to 6 months, cats with tumors 2 to 3 cm in diameter have a typical life expectancy of about two years, and cats with tumors less than 2 cm in diameter generally survive more than three years.
Prognosis — Conventional chemotherapy results in total remission in approximately 60 - 90 % of cases with a median survival time of 6 - 12 months.
Monitoring for bone marrow suppression is needed with a medication this strong, but in one study with 10 affected dogs all were able to achieve remission and median survival time was 531 days.
Dogs with tumors less than or equal to 3 cm in diameter prior to surgery had a median survival time of 31 months.
However, in a separate study, 35 % of dogs benefited from piroxicam and mitoxantrone and showed a median survival time of 291 days.
Tumors removed when they are less than 0.8 inches (2 cm) in diameter have a median survival time of 4.5 years.
In the 50 % of cats that showed at least some response to therapy, median survival time increased to 150 to 180 days as opposed to 75 to 86 days in the 50 % that did not responIn the 50 % of cats that showed at least some response to therapy, median survival time increased to 150 to 180 days as opposed to 75 to 86 days in the 50 % that did not responin the 50 % that did not respond.
But in case of oral metastasis, the median survival time has been estimated at 16 - 24 months.
In the 50 % of cats that showed at least some response to therapy, median survival time increased to 150 - 180 days as opposed to 75 - 86 days in the 50 % that did not responIn the 50 % of cats that showed at least some response to therapy, median survival time increased to 150 - 180 days as opposed to 75 - 86 days in the 50 % that did not responin the 50 % that did not respond.
I can't recall seeing a study that gave a median or average survival time for this condition but my impression is that you are basically correct in your assessment of the how well steroids work.
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