Sentences with phrase «mediated responses to infection»

Not exact matches

The rate and severity of illness to established infections such as influenza, varicella zoster virus (shingles), Streptococcus pneumonia and tetanus is also increased in the older population.2 - 4 Increased illnesses correlates with lower cell - mediated immunity and / or lower antibody responses to these infections in the elderly.

Similar to these projects, IDRI's subunit tuberculosis vaccine, ID93, also utilizes adjuvants that induce a cell - mediated immune response, which is required for protection against M. tuberculosis infection in low dose aerosol models of TB.

He and his colleagues were the first to demonstrate that human antigen - specific T cell clones could be isolated and expanded in vitro and then re-infused into patients to prevent or treat viral infections and to mediate therapeutic responses in patients with cancer.

Through long - established collaborations in Durban and Kimberley, these studies in particular seek to define: the immune responses that are effective in control of HIV infection; the impact of HLA - mediated selection pressure on HIV at the individual and population level; the mechanisms of HIV non-pathogenicity; the nature and consequences of ontogeny of the virus - specific immune response; and finally the prospects for interventions including antiretroviral therapy, alone or in combination with broadly neutralising antibodies and / or T - cell vaccines, to achieve HIV eradication.

This allows the vaccine to mimic natural infection, while taking advantage of the cat's entire immune system and prompting a broad humoral and cell - mediated response.