Scientists at The Wistar Institute Melanoma Research Center have made huge strides in understanding the biology that underlies this disease, from basic genetics to the study of
melanoma cell interaction with the microenvironment and new concepts that describe the stem cell - like abilities of melanoma to evade treatment.
Not exact matches
Metastatic
melanoma is the deadliest of the skin cancers and the mechanisms that govern early metastatic growth and
interactions of metastatic
cells with the brain microenvironment remain shrouded in mystery.
Weeraratna's team used an artificial skin reconstruct model to recreate the
interactions of
melanoma cells with either a young or aged tumor microenvironment.
They found that besides traveling in the bloodstream,
melanoma cells could also move along the abluminal, or outside, surface of blood vessels by way of angiotropism, a biological
interaction between the cancer
cells and the blood vessel
cells.