The mission of the Sequencing and
Microarray Facility is to support genomics research at MDACC by providing investigators with access to state - of - the - art instrumentation and a high level of technical expertise in a centralized facility, thereby minimizing the duplication of expensive equipment, maintaining technical excellence and enhancing research collaborations.
You are requesting access to the MD Anderson Cancer Center's MDACC Sequencing and
Microarray Facility (SMF).
We work very closely with the Sequencing and
Microarray Facility (SMF) and the DNA / RNA samples extracted from us can be submitted directly from our core to SMF across the hallway.
The Sequencing and
Microarray Facility provides essential genomic analysis services to support researchers in basic science, translational, and populationbased research programs
Not exact matches
Working at a
microarray core
facility is not where many of us thought we would be today, simply because
microarrays were not as popular (or even around!)
We are now expanding this
facility to not only include state - of - the - art protein domain
microarrays, but also to allow the further characterization of these protein - protein interactions in cells.
Services provided by EMBL Heidelberg include the Core
Facilities which provide internal users, collaborators and visitors with access to excellent
facilities for high - throughput analysis including
microarrays, protein production, mass spectrometry, DNA sequencing, advanced light and electron microscopes and chemical genomics.
For gene expression analysis,
microarrays were performed by the DKFZ Genomics and Proteomics core
facility (Heidelberg, Germany).
The
facility collaborates with various research projects using flow cytometric techniques to isolate and purify cells and chromosomes for structural and functional studies, sequencing,
microarrays as well as fluorescence insitu hybridisation (FISH) experiment.
To gain a deeper understanding of the cellular response of the two neurotoxins, the researchers applied global quantitative proteomics at the U.S. Department of Energy's national user
facility — the Environmental Molecular Sciences Laboratory — and
microarrays at UCLA to assay the protein and gene levels, respectively, for both neurotoxins.
Finally, RNA samples were prepared following the same procedure and subsequent
microarray analyses were performed in a central
facility using Affymetrix Mouse 430 v. 2 arrays.
The study, «Preferential Recognition of Avian - Like Receptors in Human Influenza A H7N9 Viruses,» received support from the National Institutes for Health (R56 AI099275), the Skaggs Institute for Chemical Biology, the Scripps
Microarray Core
Facility, the Centers for Disease Control and the Netherlands Organization for Scientific Research.
In addition, surrounding laboratory spaces of Dr. Sykes» collaborators offer access to
facilities and expertise in robotic nucleic acid extraction, real - time PCR, confocal microscopy, flow cytometry,
microarray technology, and medical mycology.