Sentences with phrase «microbicides as»

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As reported online this week in Science and in a presentation at the 18th International AIDS Conference in Vienna, of the 444 women who received a placebo gel, 60 became infected with HIV versus 38 infections in the 445 women who received the microbicide.

These include voluntary male circumcision — now recommended by the World Health Organization and Joint United Nations Programme on HIV / AIDS as a preventive strategy — as well as vaginal microbicides and oral pre-exposure prophylaxis, all of which confer only partial protection against HIV.

The researchers decided to test a microbicide that contains glycerol monolaurate (GML), a fatty acid that has proven safe in many products: It's used as a fiber finish in tampons and also as an emulsifier in many foods and cosmetics.

The failure of first - generation microbicides has led the field to largely abandon the strategy behind them: that HIV could be stopped by compounds, such as soaps, that disable the virus without specifically attacking it.

In addition to the expanded use of ARVs in new modalities such as pre-exposure prophylaxis and microbicides [1], this includes commensal microbicides [2], gene therapies [3], [4] and vaccines [5], [6], [7].

Funding: This work was supported by the European Commission sixth Frame Work Programme as part of the European Vaccines and Microbicides Enterprise (EUROPRISE), the European Commission seventh Frame Work Programme as part of the Combined Highly Active Anti-retroviral Microbicides project (CHAARM)[to RAW], the Bill and Melinda Gates Foundation as part of the Collaboration for AIDS Vaccine Discovery (CAVD grant 38637 [to RAW] and grant 1032144 [to MSS]-RRB-, and the UK Medical Research Council [RAW and AF].

Janssen GPH will also prioritise work with the International Partnership for Microbicides developing the investigational drug dapivirine for use as a monthly vaginal microbicidal ring designed to prevent sexual transmission of HIV and continue its pact with Drugs for Neglected Diseases initiative for the preclinical research of a reformulated form of flubendazole for lymphatic filariasis (elephantiasis) and onchocerciasis (river blindness), Janssen GPH is also developing a new, chewable formulation of Vermox (mebendazole) that will facilitate treatment of intestinal worms in younger children.

HIVR4P supports cross-fertilization among research on HIV vaccines, microbicides, PrEP, treatment as prevention, and other biomedical prevention approaches, while also providing a venue to discuss the research findings, questions, and priorities specific to each.

Pilar received her PhD in 2017 at the Complutense University of Madrid, where she studied immune cell dysfunction and hyperactivation in HIV / HCV coinfected patients, as well as the in vitro and in vivo activity of nanoparticles against HIV - 1 and HSV - 2 infections to prevent their transmission in humans as a topical microbicide.

«Because SEVI can so greatly enhance HIV infectivity, supplementing current HIV microbicide candidates with SEVI inhibitors, such as surfen, might increase their potency and overall effectiveness,» Greene explained.

The Resource Tracking for HIV Prevention R&D Working Group (RTWG), led by AVAC, in partnership with the International AIDS Vaccine Initiative and UNAIDS tracks trends in R&D investments and expenditures for biomedical HIV prevention options, including AIDS vaccines, microbicides, multipurpose prevention technologies, pre-exposure prophylaxis (PrEP), treatment as prevention, medical male circumcision, female condoms, HSV - 2 vaccines, HIV cure and therapeutic vaccines.

Researchers from the University of Nebraska - Lincoln have generated an «on - off switch» into a weakened form of HIV, potentially creating a new vaccine for Comprehensive exploration of research into HIV prevention, including microbicides, PrEP, PEP, condoms, circumcision and HIV treatment as prevention.

Learn about HIV prevention Comprehensive exploration of research into HIV prevention, including microbicides, PrEP, PEP, condoms, circumcision and HIV treatment as prevention.