Correspondence: Fecal
Microbiota Transplant from a Rational Stool Donor Improves Hepatic Encephalopathy: A Randomized Clinical Trial — Benjamin H Mullish — Hepatology
Fecal
microbiota transplant from a rational stool donor improves hepatic encephalopathy: a randomized clinical trial.
Rawls, J. F., Mahowald, M. A., Ley, R. E. & Gordon, J. I. Reciprocal gut
microbiota transplants from zebrafish and mice to germ - free recipients reveal host habitat selection.
Not exact matches
In the first study, scientists
transplanted fecal material
from exercised and sedentary mice into the colons of sedentary germ - free mice, which had been raised in a sterile facility and had no
microbiota of their own.
Ridaura et al. (1241214; see the Perspective by Walker and Parkhill) obtained uncultured fecal
microbiota from twin pairs discordant for body mass and
transplanted them into adult germ - free mice.
We
transplanted fecal
microbiota from adult female twin pairs discordant for obesity into germ - free mice fed low - fat mouse chow, as well as diets representing different levels of saturated fat and fruit and vegetable consumption typical of the U.S. diet.
In addition, cohousing coprophagic mice harboring
transplanted microbiota from discordant pairs provides an opportunity to determine which bacterial taxa invade the gut communities of cage mates, how invasion correlates with host phenotypes, and how invasion and microbial niche are affected by human diets.
Using fecal
transplants, researchers transferred
microbiota from IBS patients with or without anxiety into germ - free mice.
Young and colleagues used DNA sequencing to study the composition and structure of fecal
microbiota (bacteria) in stool samples
from 14 patients before and two to four weeks after fecal
transplant.
To define a relationship between gut bacteria and the efficacy of ACT, the researchers
transplanted fecal
microbiota from Jackson mice to Harlan mice.
Transplant of
microbiota from emulsifiers - treated mice to germ - free mice was sufficient to transfer some parameters of low - grade inflammation and metabolic syndrome, indicating a central role for the
microbiota in mediating the adverse effect of emulsifiers.
The effects of consuming emulsifiers were eliminated in mice devoid of
microbiota (germ - free mice), and
transplanting microbiota from emulsifier - treated mice to germ - free mice was sufficient to transfer alterations in intestinal epithelial cells» homeostasis, suggesting a central role played by the
microbiota in tumor development.
June 20, 2016
Microbiota affect the rate of transplant acceptance and rejection Researchers from the University of Chicago have shown that microbiota — the bacteria, viruses and other microbes living on the skin and in the digestive system — play an important role in the body's ability to accept transplanted skin and oth
Microbiota affect the rate of
transplant acceptance and rejection Researchers
from the University of Chicago have shown that
microbiota — the bacteria, viruses and other microbes living on the skin and in the digestive system — play an important role in the body's ability to accept transplanted skin and oth
microbiota — the bacteria, viruses and other microbes living on the skin and in the digestive system — play an important role in the body's ability to accept
transplanted skin and other organs.
Researchers
from the University of Chicago have shown that
microbiota — the bacteria, viruses and other microbes living on the skin and in the digestive system — play an important role in the body's ability to accept
transplanted...
For example, 2013 saw studies showing that
transplanting human fecal
microbiota into mice could induce obesity and its associated metabolic phenotypes, and human data
from a controlled study suggesting the procedure could treat recurrent C. difficileinfection.
Then you will learn more about it at the Corner
from OpenBiome, a non-profit organization that helps collect stool samples
from healthy donors to support physicians in fecal
microbiota transplants.