A proposed revision to the new DSM, due out next year, lists the following as
a mild impairment of interpersonal intimacy, and thus a criterion for the neurotic / personality disorders: the patient has the «[c] apacity and desire to form intimate and reciprocal relationships, but may be inhibited in meaningful expression and sometimes constrained by any intense emotion or conflict.
ASDs include a range of autistic behaviors, from
some mild impairment of social skills to more severe conditions where children show little awareness of the outside world.
Not exact matches
Indeed, the apparent decline in Trump's spontaneous speech — that is, the unscripted answers he gives in interviews and press conferences — was one
of the first behaviors that spurred debate about whether he was suffering cognitive decline or
mild cognitive
impairment.
A small 2009 study found that
of the 41 participants with
mild cognitive
impairment, those who had higher stress ratings also had faster rates
of cognitive decline.
Regardless
of the specific mechanism at play in our bodies, the most recent recommendations suggest that working out twice a week may be beneficial in curbing some symptoms
of mild cognitive
impairment (MCI), a stage that precedes the development
of Alzheimer's in some older people.
The «Elder Investment Fraud and Financial Exploitation Prevention Program» (EIFFE Prevention Program) educates healthcare and legal professionals to recognize when their older patients and clients may be vulnerable to or victims
of financial abuse, particularly those patients with
mild cognitive
impairment, and then to refer these at - risk patients to State Securities Regulators, local adult protective services professionals or for further screening and assistance as needed.
Randolph C, Karantzoulis S, Guskiewicz K. Prevalence and Characterization
of Mild Cognitive
Impairment of Retired National Football League Players.
The newborn screening tests don't detect
mild degrees
of hearing
impairment, so passing the screening doesn't mean your baby's hearing is perfect.
The study also linked traumatic brain injury with the onset
of neurodegenerative disorders, including
mild cognitive
impairment as well as Alzheimer's and Parkinson's diseases.
Ongoing studies at Uppsala University in Sweden have shown that the chemical agent dubbed Pittsburgh Compound - B, or PIB, is a highly accurate marker
of plaque buildup and that its abundance in the brain can predict whether patients with
mild cognitive
impairment will develop Alzheimer's — and when that decline will likely start.
They have secured funding from the German government, and after clearing regulatory hurdles, they will begin testing the effects
of THC in elderly adults with
mild cognitive
impairments.
People with
mild cognitive
impairment are at one - in - 10 risk
of developing dementia within a year — and the risk is markedly higher among those with depression.
If dozens
of human and animal studies published over the past six years are borne out by large clinical trials, nicotine — freed at last
of its noxious host, tobacco, and delivered instead by chewing gum or transdermal patch — may prove to be a weirdly, improbably effective drug for relieving or preventing a variety
of neurological disorders, including Parkinson's disease,
mild cognitive
impairment (MCI), Tourette's and schizophrenia.
People with
mild cognitive
impairment were defined as those who have a slight decline in cognition, mainly in memory in terms
of remembering sequences or organization, and who score lower on tests such as the California Verbal Learning Test, which requires participants to recall a list
of related words, such as a shopping list.
In the California Verbal Learning Test, on a scale
of 0 to 80, with 80 reflecting the best memory, the healthy participants had an average score
of 55.8, whereas those with
mild cognitive
impairment scored an average
of 40.5.
In pilot studies in France and Greece, the tool pinpointed patients with confirmed
mild cognitive
impairment 80 percent
of the time.
Now, researchers in The Netherlands have coupled machine learning methods with a special MRI technique that measures the perfusion, or tissue absorption rate,
of blood throughout the brain to detect early forms
of dementia, such as
mild cognitive
impairment (MCI), according to a new study published online in the journal Radiology.
Northwestern University's Ken Paller is already administering this type
of stimulation to middle - aged adults with
mild cognitive
impairment, often an early indicator
of Alzheimer's disease.
Their research technique
of measuring electrical brain activity using an electroencephalogram (EEG) in these brain regions also predicted
mild cognitive
impairment (MCI), a condition that is likely to develop into Alzheimer's, with 80 per cent accuracy.
Physicians have no definitive way
of identifying who has early dementia or which cases
of mild cognitive
impairment will progress to Alzheimer's disease.
[Bryan James et al., «Life Space and Risk
of Alzheimer Disease,
Mild Cognitive
Impairment, and Cognitive Decline in Old Age»]
Researchers estimate that as many as 2.1 million patients with
mild cognitive
impairment could develop Alzheimer's dementia over a two - decade period while waiting for evaluation and treatment resources after approval
of an Alzheimer's disease - modifying therapy by the federal Food and Drug Administration.
Under such a scenario, about 71 million Americans aged 55 and older would have to be screened for signs
of mild cognitive
impairment.
Accumulation
of insoluble U1 protein was seen in samples from patients with
mild cognitive
impairment (MCI), a precursor stage to Alzheimer's, but the U1 pathology was not seen in any other brain diseases that were examined.
Yonas E. Geda, M.D. and colleagues at the Mayo Clinic investigated the relationship between timing
of exercise (mid - life / 50 -65 vs. late - life / 70 and above) and risk
of new cases
of dementia in 280 older adults (median age = 81) with
mild cognitive
impairment (MCI) from the Mayo Clinic Study
of Aging, and reported on their findings at AAIC 2014.
Indeed, studies in humans indicate that exercise can preserve and possibly even enhance cognitive function in individuals with dementia or other forms
of mild cognitive
impairment,» added Dr. Christie.
People with sleep apnea, for example, a condition in which people repeatedly stop breathing at night, are at risk for developing
mild cognitive
impairment an average
of 10 years earlier than people without the sleep disorder.
In a large population - based study
of randomly selected participants in Germany, researchers found that
mild cognitive
impairment (MCI) occurred significantly more often in individuals diagnosed with a lower ankle brachial index (ABI), which is a marker
of generalized atherosclerosis and thus cumulative exposure to cardiovascular risk factors during lifetime.
Particularly interesting would be the inclusion
of a more comprehensive battery
of neuropsychological tests, so that the association
of volunteering with the risks
of various forms
of dementia and its precursor,
mild cognitive
impairment, could be ascertained,» the report concluded.
50 out
of 66 and categorized them as having «
mild to moderate» functional deficits for the purposes
of the study, and 10 other patients with FMA scores
of < 50 out
of 66 and categorized them as having «moderate to severe»
impairment.
Symptoms
of traumatic brain injury can range from the
mild, such as lingering headaches and nausea, to more severe
impairments in memory and cognition.
This will be
of particular benefit to those people who have
mild cognitive
impairments, for example older people who are still physically healthy but may have early symptoms
of dementia.»
The study, funded by the Nuffield Foundation, found 25 per cent
of its young participants who had reading difficulties showed
mild or moderate hearing
impairment,
of which their parents and teachers were unaware.
This will enable people with
mild cognitive
impairments to live more independently, and the robots will also help with activities that can improve quality
of life, such as exercise and social visits.
After administering PET scans to 4000 people previously diagnosed with either
mild cognitive
impairment (MCI) or dementia and treated for Alzheimer's to test for the presence
of amyloid plaque, only 53.3 %
of patients with MCI and 70.5 % with dementia tested positive.
«Early detection
of individuals at high risk
of developing memory and thinking problems that we call
mild cognitive
impairment (MCI) is crucial because people with MCI are at a greater risk
of developing dementia.
The intervention was also not associated with improved neurological status
of full recovery or
mild impairment at discharge for patients with or without VF.
Of these, 52 were healthy, 48 had Alzheimer's disease and 48 had
mild cognitive
impairment (MCI), but were known to have developed Alzheimer's disease 2.5 to nine years later.
In a long - term, large - scale population - based study
of individuals aged 55 years or older in the general population researchers found that those diagnosed with
mild cognitive
impairment (MCI) had a four-fold increased risk
of developing dementia or Alzheimer's disease (AD) compared to cognitively healthy individuals.
A further analysis showed that 10
of these proteins could predict whether individuals with
mild cognitive
impairment would develop Alzheimer's within a year.
Six - month studies showed twice - weekly workouts may help people with
mild cognitive
impairment as part
of an overall approach to managing their symptoms.
«Regular physical exercise has long been shown to have heart health benefits, and now we can say exercise also may help improve memory for people with
mild cognitive
impairment,» says Ronald Petersen, M.D., Ph.D., lead author, director
of the Alzheimer's Disease Research Center, Mayo Clinic, and the Mayo Clinic Study
of Aging.
In Alzheimer's disease, this loss
of synapses occurs very early on, when people still only have
mild cognitive
impairment, and long before the nerve cells themselves die.
More than 6 percent
of people in their 60s have
mild cognitive
impairment across the globe, and the condition becomes more common with age, according to the American Academy
of Neurology.
The recommendation is part
of an updated guideline for
mild cognitive
impairment published in the Dec. 27 online issue
of Neurology, the medical journal
of the American Academy
of Neurology.
Noting that the prescription
of PPIs is on the rise among middle - aged and older adults, a team
of researchers designed a new study to examine PPIs and the risk
of dementia,
mild cognitive
impairment, and Alzheimer's disease.
Both unawareness
of illness (anosognosia) and memory loss (known as
mild cognitive
impairment) can be objectively assessed using questionnaires.
As the next stage
of this research, Dr. Gerretsen will be tracking older adults with
mild cognitive
impairment who are receiving an intervention to prevent Alzheimer's dementia.
The middle and inferior temporal gyri, for example, also play roles in memory and sensory integration and have been shown to be involved in the early stages
of mild cognitive
impairment and Alzheimer's disease.
Conducting a cross-sectional study
of a large cohort
of patients with different levels
of cognitive
impairment and different disease stages, the researchers found that the amounts
of a TREM2 fragment in the cerebrospinal fluid were highest during early stages characterized by
mild cognitive
impairment symptoms.