Modifying epigenetic markers is not easy — and that's a good thing.
Not exact matches
The scientists also discovered that genes
modified only by one of the
epigenetic markers, H3K4me3, contain the DNA recipes for proteins that enable an ES cell to proliferate, or duplicate itself.
With the sequence data in hand, the scientists were able to categorize the genes into three groups, each
modified by different combinations of the two
epigenetic markers.
Determining how ES cell genes are
modified by these
epigenetic markers may explain these cells» unique characteristics, said the scientists, who are based at the Genome Institute of Singapore (GIS) and the Bioprocessing Technology Institute (BTI), both under the Agency for Science, Technology and Research (A * STAR), as well as at the National University of Singapore (NUS).