Sentences with phrase «molecular cytogenetics»

A member of a team that decoded the canine genome in 2005, Dr. Breen is recognized internationally for his research into molecular cytogenetics — the study of the structure and function of cells and chromosomes — and the

An overall theme of the Morton Laboratory is to apply evolving techniques in molecular cytogenetics to address problems in human cytogenetics, with interests including chromosomal rearrangements in constitutional and acquired cytogenetic disorders.

Research Technician in Human Molecular Cytogenetics at the Cambridge University Department of Pathology

Molecular Cytogenetics, 8:75, (2015).

Dr. Schwartz's main research interests include molecular cytogenetics, particularly understanding the causes and effects of chromosomal abnormalities.

Along with other clinical science departments, such as haematology, immunology, microbiology, molecular cytogenetics, histopathology, and medical physics, clinical biochemists carry out the diagnostic services that provide valuable information to doctors and other health care professionals within the National Health Service (NHS).

The primary goal of this facility is to offer conventional and molecular cytogenetic services, including species identification, karyotyping, analysis of genomic instability, fluorescence in situ hybridization and spectral karyotyping

Allele - specific PCR, molecular cytogenetic studies, microsatellite PCR, Affymetrix single nucleotide polymorphism array analyses, and colony assays were undertaken on subgroups of patients.

Not exact matches

Geneticists passed from the formal genetics of individuals to cytogenetics at the cellular level, to the biochemistry of DNA in duplication and in protein synthesis at the molecular level, back to physiological and developmental genetics again at the cellular level and back to the level of the individual in behavioral genetics and beyond the individual to population genetics and the theory of evolution.

Then, Scott contacted co-author Dr. Seema Lalani, associate professor of molecular and human Genetics at Baylor and assistant laboratory director of cytogenetics at Baylor Genetics.

B.S. in Biology, Ph.D. in Human Genetics, Post-doc in Molecular Genetics, ABMG certification in Clinical Cytogenetics, Ph.D..

A large variety of methods is used including genetic, molecular and cytogenetic techniques, fluorescence in situ hybridisation and DNA «combing», as well as high throughput sequencing approaches such as DNA - seq for mutation landscape analyses, RNA - seq for transcriptome analyses and ChIP - seq mapping of chromatin - associated proteins and their genome - wide modulation in response to DNA damages.

Among patients with favorable cytogenetic and molecular features, the point estimates for disease - free survival and overall survival were approximately 1, indicating no benefit of a fifth course of chemotherapy, Getz said.

However, among patients who had uninformative cytogenetic or molecular features but who were MRD < 0.1 % at the end of induction I, the disease - free survival (HR, 1.86; 95 % CI, 1.18 — 2.92; P =.008) and overall survival (HR, 1.91; 95 % CI, 1.01 — 3.61; P =.046) were almost twice as high in patients who received five treatment courses compared with four courses.

Exciting advances in fluorescence in situ hybridization and array - based techniques are changing the nature of cytogenetics, in both basic research and molecular diagnostics.

The high resolution that is achieved by these techniques, particularly by microarray technologies such as array comparative genomic hybridization, is blurring the traditional distinction between cytogenetics and molecular biology.

Enzo Clinical Labs also provides clinical diagnostic services that allow Enzo to capitalize on its extensive advanced molecular and cytogenetic capabilities and the broader trends in predictive and personalized diagnostics.

The following institutions contributed to the study: Technical University of Munich (Central Institute of Translational Cancer Research, Clinic and Policlinic for Internal Medicine II, Institute of Pathology), DKTK and DKZF Heidelberg; The Wellcome Trust Sanger Institute, Cambridge; Ludwig - Maximilians Universität (Anthropology & Human Genomics und Innere Medizin II des Klinikums Großhadern), Helmholtz Zentrum München (Research Unit Radiation Cytogenetics); Universidad de Oviedo (Bioquímica y Biología Molecular, IUOPA und CINN - CSIC), Instituto de Medicina Oncológica y Molecular de Asturias (IMOMA), Oviedo, University of Cambridge (Department of Veterinary Medicine), Instituto de Medicina Oncológica y Molecular de Asturias, Instituto de Biomedicina y Biotecnología de Cantabria.

Topics explored by AJHG include behavioral genetics, biochemical genetics, clinical genetics, cytogenetics, dysmorphology, gene therapy, genetic counseling, genetic epidemiology, genomics, immunogenetics, molecular genetics, neurogenetics, and population genetics.

She is board - certified in Clinical Cytogenetics and Clinical Molecular Genetics and has nearly 20 years» experience overseeing CAP / CLIA - certified clinical genetics laboratories.

Those with uninformative cytogenetic or molecular markers with negative minimal residual disease at the end of induction were noted to experience the most benefit (nearly 2-fold benefit from receiving a fifth dose of chemotherapy) vs. those with favorable cytogenetic and molecular features who did not experience benefit from receiving a fifth dose of therapy.

His research focused on various cancers and the genetics of inherited diseases, where he directed the Clinical Cytogenetic and Molecular Diagnostics Laboratories, and where he taught numerous courses in the School of Medicine.

Ongoing: Posters Open for Viewing, Exhibit Hall, South Building Topics: Bioinformatics and Computational Approaches, Posters 1181 - 1457; Molecular and Cytogenetic Diagnostics, Posters 2370 - 2601

Medical Genetics, Clinical Cytogenetics and Clinical Molecular Genetics.

The goal of the genetics course in the Foundation Block is to train the student in principles of inheritance, and provide an introduction to molecular genetics and cytogenetics.

He is a medical geneticist, pediatrician, and child neurologist, certified by the American Board of Medical Genetics and Genomics (clinical genetics, clinical cytogenetics, and clinical molecular genetics), American Board of Pediatrics, and American Board of Psychiatry and Neurology (child neurology).

A Look at History, Morphology, Cytogenetics, and Molecular Studies