Open - Source Automated Parahydrogen Hyperpolarizer for
Molecular Imaging Using 13C Metablic Contrast Agents.
The Congress, Co-sponsored by the Society of Nuclear Medicine and Molecular Imaging (SNMMI) and Johns Hopkins Medicine, welcomed physicians, chemists, physicists, technologists, and all scientists and clinicians interested in translational research and current state - of - the - art
molecular imaging using Ga - 68 PET radiopharmaceuticals and radionuclide therapy.
Not exact matches
Under the tutelage of her PhD supervisor, Southampton's Sumeet Mahajan, Professor in
Molecular Biophotonics &
Imaging in Chemistry & Institute for Life Sciences (IfLS), Catarina is
using ultra-fast lasers to achieve the same effect but in a less invasive way.
Earlier, for his Ph.D., he
used his physics training to study biological interactions at the
molecular resolution — but for his postdoc he changed approaches dramatically, turning to cell biology and applying his skills to the development of high - resolution functional
imaging of DNA transcription in living cells.
FDG - PET, one of the only
molecular imaging techniques routinely
used in oncology, employs a glucose - like probe, FDG, with a radioactive isotope of fluorine attached as a beacon.
But new
molecular imaging, which can be
used to complement the biopsy and is noninvasive, can provide added benefit in certain cases, especially when multiple examinations are needed.
«Our findings demonstrate the feasibility of classifying cancerous and normal breast tissues
using DESI mass spectrometry
imaging,» said Nathalie Agar, PhD, director of the Surgical Molecular Imaging Laboratory, BWH Departments of Neurosurgery and Radiology, senior study
imaging,» said Nathalie Agar, PhD, director of the Surgical
Molecular Imaging Laboratory, BWH Departments of Neurosurgery and Radiology, senior study
Imaging Laboratory, BWH Departments of Neurosurgery and Radiology, senior study author.
For the first time, scientists have
used Positron Emission Tomography (PET)
imaging to study brain inflammation following Zika virus infection in mice, according to a study recently published online in the journal Molecular Imaging and B
imaging to study brain inflammation following Zika virus infection in mice, according to a study recently published online in the journal
Molecular Imaging and B
Imaging and Biology.
Richards - Kortum's work brings together nanotechnology,
molecular imaging, and microfabrication to address global health challenges by developing low - cost medical technologies — such as a portable microendoscope to diagnose and treat cervical cancer — for
use on the ground in low - resource settings around the world.
Gijs van der Schot, a Ph.D. student in the Department of Cell and
Molecular Biology at Uppsala, will describe the researchers» new approach to
imaging during the AVS 62nd International Symposium & Exhibition, held Oct. 18 - 23 in San Jose, Calif. «The X-ray laser we
use for our work, the LCLS, is a fascinating machine — because of the physical principles behind it and the precise engineering of its parts — that produces very bright and ultra-short pulses,» he said.
Current
molecular breast
imaging systems
use a traditional collimator, which is essentially a rectangular plate of dense metal with a grid of holes, to «filter» the gamma rays for the camera.
They found that
using the VASH collimator with an existing breast
molecular imaging system, they could get six times better contrast of tumors in the breast, which could potentially reduce the radiation dose to the patient by half from the current levels, while maintaining the same or better image quality.
C.elegans has been
used for decades as a model animal to study the genetic and
molecular underpinnings of neurological disorders through a number of techniques including bio
imaging, electrophysiology and behavior.
Jimmy Bell heads the
molecular imaging group at Imperial College London, where he pioneered body fat
imaging using MRI.
The study mostly makes
use of cultured cortical neurons from rats, exploiting a wide array of
molecular and
imaging techniques to probe the mitochondrial function and well - being of neurons manipulated to model Wolfram syndrome.
«
Molecular imaging of neuroendocrine tumors optimizes radiotherapy dose: Study shows the
use of PET and SPECT tailors radionuclide treatment for neuroendocrine cancer patients and reduces the risk of toxicity.»
Scientists are taking preemptive action by
using already available
molecular imaging systems to determine the optimal dose of one such peptide - receptor radionuclide therapy known as yttrium - 90 DOTA0 - Tyr3 - octreotide (Y - 90 DOTATOC).
The project, which brings together physical oceanographers, marine biologists,
imaging specialists,
molecular biologists, bioinformaticists and modelers,
uses what it calls a «holistic» and «study it all» approach, analyzing many species at once
using a variety of methods, many of them automated.
Specifically, the
imaging agents developed in the laboratory for
use in fluorescence
molecular tomography, are now even being translated into the clinic for human diagnostic applications.
Using the Nanofabrication and
Imaging and Manipulation facilities at the
Molecular Foundry to analyze the patterns, the researchers saw improvements in the smoothness of lines created by the photoresist, even as they shrunk the width.
The Clinical Trials Network (CTN) provides tools and resources to promote faster, more cost - effective drug development and increase the availability and performance of
molecular imaging radiopharmaceuticals for
use in the clinic.
«Deciphering the Aqueous Chemistry of Glyoxal Oxidation with Hydrogen Peroxide
Using Molecular Imaging.»
We will
use molecular, histological, calcium
imaging and electrophysiological methods to characterize the sensitivity of these channels to membrane stretch by mimicking the effect of IOP on RGC perikarya and axons.
Using a combination of
molecular biology, biochemical and novel multi-dimensional digital
imaging approaches we study in real - time complex multi dimensional signal integration during the interaction of T cells with live antigen - presenting cells.
The profession of nuclear medicine and
molecular imaging has evolved over the past several years, and continues to evolve to include
imaging and therapy beyond the sole
use of radioactive materials.
Methods: The international research team
used surface science and
imaging capabilities at DOE's Environmental
Molecular Sciences Laboratory at Pacific Northwest National Laboratory.
Finally, the HZI will help develop in vivo
imaging technologies to characterize (i) vaccine biodistribution and persistence, and (ii) cellular and
molecular changes at the injection site and in draining lymphoid tissues, helping to refine the
use of animal models.
Andrew Huberman, PhD: Each of our labs
uses a variety of techniques such as anatomy or
imaging, or physiology,
molecular biology and genetics but no two labs are exactly the same; so what's really great about the Catalyst for a Cure initiative is that each lab is very expert in one or a few of those different techniques.
Virginia Altoe imaged the nanowires
using transmission electron microscopy in the
imaging facility of the
Molecular Foundry.
Using single - molecule
imaging, super-resolution microscopy and various biophysical and
molecular approaches she will explore how gene expression in living cells works.»
Meguro, Japan (Scicasts)- Tumour detection
using targeted fluorescent
imaging probes is a promising technology that takes advantage of specific
molecular events occurring in cancer tissues.
We are
using live
imaging, transgenic reporters of osteoblast gene expression and targeted RNAseq approaches to identify the
molecular regulators of progressive osteoblast differentiation during expansion of the skull.
Structures composed of dimers and multimers have been extensively
used in chemistry [78, 79], especially in
molecular imaging [80].
This research makes
use of single -
molecular fluorescence
imaging technology to visualize and analyze the behavior of exogenous DNA that were introduced into the cell from outside.
Importantly, the
molecular imaging models that are developed can be employed to accelerate the discovery of targets and drugs for therapeutic intervention, and biomarkers that could be
used for early diagnosis.
We are
using live cell
imaging, single cell analysis and gene editing to resolve the
molecular determinants of human epidermal progenitor cell division outcomes (two progenitors, two differentiating cells or one or each) and the mode of cell division (maintenance mode vs repair mode).
Molecular imaging methods that visualize the structure and function of the living body are widely
used in clinical and biomedical research settings.
The Dotiwala laboratory
uses cellular,
molecular, biochemical and omics approaches, as well as sophisticated in vivo
imaging, to dissect the mechanism by which cell - based immunity (neutrophils, macrophages and killer lymphocytes) is activated in the presence of different pathogenic bacteria, such as intra - and extracellular bacteria, fungi and protozoa.
This includes the diagnostic, therapeutic or investigational
use of radionuclides or other
molecular imaging technologies.
Clinical Trials Research and Billing First in Human / Early Phase PET in Oncology Case - Based Dose Reduction in Pediatric Nuclear Medicine: Practical and Necessary Radioiodine Therapy for Hyperthyroidism: The State of the Art Spondylodiscitis: Role of
Imaging for Diagnosis and Monitoring Treatment Response Current Status and Future Prospects: PET and SPECT Instrumentation Alternative Payment Models and Value - Based Health Care: Nuts and Bolts Maximal Tolerated Activity of Radioactive Iodine for Metastatic Thyroid Cancer Teaching Old Radiopharmaceuticals New Tricks Intraoperative Detection Devices and Probes
Molecular Imaging of Lung Inflammation Standardization of Advanced PET / SPECT Data Acquisition and Analysis Thyroid Cancer Management: Novel Therapeutics and Management Options Targeting Radionuclide Therapy in Various Non-Malignant Arthritic Conditions
Using Radiosynoviorthesis (RSO) Are You Prepared for a Radiation Accident?
・
Use of single -
molecular fluorescence
imaging technology to elucidate the fate of DNA introduced into a living cell.
Molecular imaging includes the field of nuclear medicine, which
uses very small amounts of radioactive materials (radiopharmaceuticals) to diagnose and treat disease.
By
using a combination of genetics, fix and live
imaging, cell biology and
molecular biology techniques we are exploring the consequences of polyploidy in the brain and epithelial tissues of Drosophila.
Nuclear medicine — a vital component of the rapidly emerging field of
molecular imaging — is a medical specialty that
uses small amounts of radioactive materials bound to special compounds (radiopharmaceuticals) in combination with
imaging instrumentation that examine
molecular processes in the body to detect and evaluate disease, such as brain disorders, heart disease and cancer.
This result gives rise to the possibility of
using nanodiamonds, suitably treated to attach themselves to targets that we would like to detect, as MRI markers for
molecular imaging applications.
When the
molecular imaging research community improves image standardization, there is a greater likelihood of harmonization; i.e., that a specific
imaging procedure can be
used as a marker across clinical trials; not simply for one clinical trial.
My research made
use of a range of cell culture, cell
imaging,
molecular and bioinformatic techniques, to investigate the evolution of hydrogenosomes (mitochondrial homologues that make hydrogen) in some anaerobic protists, found in a variety of naturally anoxic habitats.
We study these questions
using molecular, cellular and transgenic approaches as well as real time in vitro and in vivo
imaging.
The team will continue to develop and test an
imaging - based biomarker that can be
used in a clinical setting to enable us to understand the
molecular changes to the ganglion cells, so we can detect the disease very early on.
The Melanoma / Skin Cancer Program provides expert diagnosis and staging
using advanced
imaging technologies and research - based
molecular testing including: