Sentences with phrase «molecular libraries screening»

Not exact matches

A new technique of direct binding of radioactive DNA was used to screen a complementary DNA expression library from the BJAB cell line in lambda gt11 phage to derive molecular cDNA clones representing a putative B lymphocyte - specific octamer binding protein.

Dr. Rubin said Curis had established a screening assay for SMN levels for a molecular library, first in fibroblasts from an SMA patient.

The identification of disease signatures will enable screens of small molecule libraries to delineate molecular targets that modulate these disease signatures and identify new diagnostic and therapeutic leads for schizophrenia and bipolar disorder.

The second area is pharmacology based on automated screening of large libraries of compounds with therapeutic potential, following modeling of molecular mechanisms associated with diseases, as revealed by the study of pluripotent stem cells from affected donors.

He was a postdoctoral scientist at Applied Molecular Evolution, where he produced and screened random peptide phage display libraries with soluble empty mouse CD1 (mCD1) to identify a peptide - binding motif for MHC Class I like receptors.