Sentences with phrase «molecular tumor profiling»

In 2011, she joined the institution's molecular diagnostics laboratory where she has been developing translational next generation sequencing assays and bioinformatics workflows for the Molecular Tumor Profiling Lab of the Yale Cancer Center.

Not exact matches

Traditional genetic approaches together with the new wealth of genomic information for both human and model organisms open up strategies by which drugs can be profiled for their ability to selectively kill cells in a molecular context that matches those found in tumors.

Caris performed the molecular profiling on 48,733 solid tumor samples to assess the prevalence of homologous recombination deficiency in about 20 different types of solid tumors.

This webinar will explore recent progress and future directions in translational and clinical efforts centered on checkpoint modulators and combination therapies matched to the molecular profile of individual tumors and the genetic background of patients.

Rather than simply identifying a cancer by location or tissue type, researchers now use advanced molecular profiling tests to characterize tumors, the proteins they express and the novel mutations they develop — known as neoantigens.

Many of our brain tumor clinical trials include analysis of the molecular profiles of patients» tumors.

In the next decade, molecular research is going to further develop along five lines: predictive medicine, that investigates the genetic conditions predisposing to tumor risk; early molecular diagnosis; the evaluation of each patient's prognosis based on his / her genetic profile, in other words, the analysis of what kind of mutation affects the DNA of altered cells; the investigation of the individual response to drugs, based on our genetic knowledge; «smart drugs», molecules able to hit the target in a selective way, killing only the deprogrammed cells.»

«Therefore, any potential promising results get diluted because novel therapies are not administered to those select patients who are most likely to respond, based on their tumors» molecular profile.

Data generated by the working group, which includes molecular profiling of over 10,000 tumors across 33 tumor types as well as a series of results on immune - tumor interaction and response mechanisms, will provide rich characterizations of the relationship between tumors and the immune microenvironment and its impact on patient outcomes.

To develop the methodology, the group analyzed the molecular profiles of human embryonic stem cells and compared them with data for 12,000 samples of 33 different tumor types held by The Cancer Genome Atlas (TCGA), a U.S. public database.

Caris, under the guidance of Baker, provided the tissue and ran the molecular profiling on solid tumor samples collected from across the United States.

The study found that it's now feasible in dogs to collect a tumor sample and perform molecular profiling in less than a week's time, a clinically practical window.

In precision medicine, molecular profiling of an individual patient's tumor is used to identify genetic mutations that drive that...

If you are searching for a proven Clinical Trials Doctor with more than 20 years» experience, who will generate innovation and provide compelling and innovative molecular profiling of patients» tumors and possible treatments for refractory cancers, please contact me to arrange an interview.

Co-author of the Bisgrove Phase I clinical trial published in fall 2009: A Pilot Study Using Molecular Profiling of Patients» Tumors to Find Potential Targets and Select Treatments for their Refractory Cancers.